Serum Cotinine (BCS)
Blood samples for the determination of circulating cotinine levels were drawn 1 to 2 days before and again 28 days after viral challenge.
Cotinine levels were measured in serum by gas chromatography1.
1Feyerabend, C., & Russell, M. A. H. (1990). A rapid gas-liquid chromatographic method for the determination of cotinine and nicotine in biological fluids. Journal of Pharmacy and Pharmacology, 42, 450-452.