Carnegie Mellon University
Matyjaszewski Polymer Group  ›  Former Members  ›  Dr. Siva Shanmugam

Siva Shanmugam

Siva Shanmugam

Postdoctoral Associate

Address
Carnegie Mellon University
4400 Fifth Avenue
Mellon Institute
Pittsburgh, PA 15213

Education

Doctor of Philosophy in Chemical Engineering, University of New South Wales, Sydney, Australia, 2017

Bachelor of Science, Biochemistry (summa cum laude), Case Western Reserve University, Cleveland, Ohio, 2013

Research

Photopolymerization, electrochemistry, material (hydrogel), extraction and purification of protein, DNA, and natural products

Research Experience

Academia:

  1. University of New South Wales (UNSW), Sydney, Australia, 2014-2017
    Thesis: Development of light mediated RAFT radical photopolymerization technique for synthesis of functional materials
    Advisor: Prof. Cyrille Boyer
  2. University of California, Santa Barbara, California
    Exchange Scholar in Hawker Research Group, Dow Materials Research Lab, 2016
    Project: Separation of sequence-defined synthetic oligomers synthesized through single unit monomer insertion (SUMI) via photoredox polymerization
    Advisor: Prof. Craig Hawker
  3. Case Western Reserve University, Cleveland, Ohio, 2010-2013
    Thesis: Characterization of chemical reaction pathways of novel antibiotic candidates in beta-lactamase proteins via Raman spectroscopy
    Advisor: Prof. Paul and Marianne Carey

Industrial projects:

  1. Extraction of active ingredients from plants for cosmetic applications (2017)
    Advisor: Prof. Franck Lucien (UNSW)
  2. Provided product analysis (primarily plastics) and consultations to different companies (2014-2017)
    Manager: Mr. Eh Hau Pan

Presentations

  1. Pacifichem 2015, Hawaii, December 2015 – Winner of highly competitive Student Poster Competition
  2. Pacific Polymer Conference (PPC14), Hawaii, December 2015
  3. 35th Australasian Polymer Symposium, Gold Coast, Queensland, July 2015

Research Highlights

Scientific Magazines

  1. Chemistry in Australia (November 2015 article, page 13) http://chemaust.raci.org.au/sites/default/files/pdf/2015/CiA_Nov2015.pdf)
  2. Chemistry in Australia, (May 2015 article, page 14) http://chemaust.raci.org.au/sites/default/files/pdf/2015/CiA_May2015_final.pdf)
  3. Chemistry in Australia, (October 2015 article, page 13)
    http://chemaust.raci.org.au/sites/default/files/pdf/2015/CiA_Oct2015.pdf
  4. Chemistry in Australia, (April 2016 article, page 14)
    http://chemaust.raci.org.au/sites/default/files/pdf/2016/CiA_April%202016_final.pdf

Websites

  1. Chemistry World (https://www.chemistryworld.com/research/spinach-chlorophyll-activates-polymer-production-line/8055.article)
  2. Engineers Australia (https://www.engineersaustralia.org.au/portal/news/bio-mimicry-research-leads-creation-polymers-using-near-infrared)

Publications

Peer-reviewed articles:

  1. Shanmugam, S., Xu, J., Boyer, C (2017). Photocontrolled Living Polymerization Systems with Reversible Deactivations through Electron and Energy Transfer. (Invited Review) Macromolecular Rapid Communications 2017, 38 (13), 1700143 (1-40).
  1. Shanmugam, S., J. Xu and C. Boyer (2017). Photoinduced Oxygen Reduction for Dark Polymerization. Macromolecules 2017, 50 (5), 1832–1846.
  1. Xu, J., C. Fu, S. Shanmugam, C. J. Hawker, G. Moad and C. Boyer (2017). Synthesis of Discrete Oligomers by Sequential PET-RAFT Single-Unit Monomer Insertion. Angewandte Chemie International Edition 2017, 129 (29), 8496-8503.
  1. Shanmugam, S., J. Xu and C. Boyer (2017). Living Additive Manufacturing (First Reactions). ACS Central Science 2017, 3 (2), 95-96.
  1. Shanmugam, S., J. Xu and C. Boyer (2016). Aqueous RAFT Photopolymerization with Oxygen Tolerance. Macromolecules 2016, 49(24), 9345-9357.
  1. Shanmugam, S., J. Xu and C. Boyer (2016). A logic gate for external regulation of photopolymerization. Polymer Chemistry 2016, 7(42), 6437-6449.
  1. Yeow, J., S. Shanmugam, N. Corrigan, R. P. Kuchel, J. Xu and C. Boyer (2016). A Polymerization-Induced Self-Assembly Approach to Nanoparticles Loaded with Singlet Oxygen Generators. Macromolecules 2016, 49(19), 7277-7285.
  1. Shanmugam, S., & Boyer, C. (2016). Organic photocatalysts for cleaner polymer synthesis. Science 2016, 352(6289), 1053-1054.
  1. Ren, J. M., T. G. McKenzie, Q. Fu, E. H. H. Wong, J. Xu, Z. An, S. Shanmugam, T. P. Davis, C. Boyer and G. G. Qiao (2016). Star Polymers. Chemical Reviews 2016, 116(12), 6743-6836.
  1. Corrigan, N., Shanmugam, S., Xu, J., & Boyer, C. (2016). Photocatalysis in organic and polymer synthesis. Chemical Society Reviews 2016, 45 (22), 6165-6212.
  1. Xu, J., Shanmugam, S., Fu, C., Aguey-Zinsou, K.-F., & Boyer, C. (2016). Selective Photoactivation: From a Single Unit Monomer Insertion Reaction to Controlled Polymer Architectures. Journal of the American Chemical Society 2016, 138(9), 3094-3106.
  1. Shanmugam, S.; Xu, J.; Boyer, C.(2016), Light-Regulated Polymerization under Near-Infrared/Far-Red Irradiation Catalyzed by Bacteriochlorophyll a. Angewandte Chemie International Edition 2016, 55 (3), 1036–1040.
  1. Boyer, C.; Corrigan, N. A.; Jung, K.; Nguyen, D.; Nguyen, T.-K.; Adnan, N. N. M.; Oliver, S.; Shanmugam, S.; Yeow, J.(2015), Copper-Mediated Living Radical Polymerization (Atom Transfer Radical Polymerization and Copper(0) Mediated Polymerization): From Fundamentals to Bioapplications. Chemical Reviews 2015, 116 (4), 1803–1949.
  1. Xu, J., S. Shanmugam, and C. Boyer (2015), Organic Electron Donor–Acceptor Photoredox Catalysts: Enhanced Catalytic Efficiency toward Controlled Radical Polymerization. ACS Macro Letters 2015, 4(9), 926-932.
  1. Shanmugam, S. and C. Boyer (2015), Stereo-, Temporal and Chemical Control through Photoactivation of Living Radical Polymerization: Synthesis of Block and Gradient Copolymers. Journal of the American Chemical Society 2015, 137(31), 9988-9999.
  1. Shanmugam, S., J. Xu, and C. Boyer (2015), Exploiting Metalloporphyrins for Selective Living Radical Polymerization Tunable over Visible Wavelengths. Journal of the American Chemical Society 2015, 137(28), 9174-9185.
  1. Xu, J.; Shanmugam, S.; Duong, H. T.; Boyer, C., Organo-photocatalysts for photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization. Polymer Chemistry 2015, 6 (31), 5615-5624.
  1. Che, T.; Rodkey, E. A.; Bethel, C. R.; Shanmugam, S.; Ding, Z.; Pusztai-Carey, M.; Nottingham, M.; Chai, W.; Buynak, J. D.; Bonomo, R. A.; van den Akker, F.; Carey, P. R. (2015), Detecting a Quasi-stable Imine Species on the Reaction Pathway of SHV-1 β-Lactamase and 6β-(Hydroxymethyl)penicillanic Acid Sulfone. Biochemistry 2015, 54 (3), 734-743.
  1. Shanmugam, S., J. Xu, and C. Boyer (2015), Utilizing the electron transfer mechanism of chlorophyll a under light for controlled radical polymerization. Chemical Science 2015, 6(2), 1341-1349.
  1. Shanmugam, S., J. Xu, and C. Boyer (2014), Photoinduced Electron Transfer–Reversible Addition–Fragmentation Chain Transfer (PET-RAFT) Polymerization of Vinyl Acetate and N-Vinylpyrrolidinone: Kinetic and Oxygen Tolerance Study. Macromolecules 2014, 47(15), 4930-4942.
  1. Xu, J.; Jung, K.; Atme, A.; Shanmugam, S.; Boyer, C. (2014), A Robust and Versatile Photoinduced Living Polymerization of Conjugated and Unconjugated Monomers and Its Oxygen Tolerance. Journal of the American Chemical Society 2014, 136 (14), 5508-5519.
  1. Heidari Torkabadi, H.; Che, T.; Shou, J.; Shanmugam, S.; Crowder, M. W.; Bonomo, R. A.; Pusztai-Carey, M.; Carey, P. R.(2013), Raman Spectra of Interchanging β-Lactamase Inhibitor Intermediates on the Millisecond Time Scale. Journal of the American Chemical Society 2013, 135 (8), 2895-2898.
  1. Che, T.; Bonomo, R. A.; Shanmugam, S.; Bethel, C. R.; Pusztai-Carey, M.; Buynak, J. D.; Carey, P. R. (2012), Carboxylation and Decarboxylation of Active Site Lys 84 Controls the Activity of OXA-24 β-Lactamase of Acinetobacter baumannii: Raman Crystallographic and Solution Evidence. Journal of the American Chemical Society 2012, 134 (27), 11206-11215.

Book chapter:

Jiangtao, X.; Shanmugam, S.; Nathaniel Alan, C.; Cyrille, B (2015), Catalyst-Free Visible Light-Induced RAFT Photopolymerization. In Controlled Radical Polymerization: Mechanisms, American Chemical Society: 2015; Vol. 1187, 247-267.