 
      
          Areas of Research at Mellon College of Science
Sustainability Science
CMU research scientists are developing smart solutions for urgent sustainability issues. Their work advances our understanding of changes in the environment and builds cleaner technologies that safeguard life on Earth.
 
      
          Stefan Bernhard
Focus areas: Research in luminescent materials, solar fuels, organic photovoltaics, organic light-emitting devices, circular polarized luminescence
 
      
          Terrence Collins
Focus areas: Green chemistry, green oxidation catalysis in water, inorganic chemistry, biomimetic chemistry of peroxidase enzymes, mechanisms of oxidation catalysis, novel approaches to water purification
 
      
          Neil Donahue
Focus areas: Atmospheric chemistry, organic aerosol, kinetics, reaction dynamics, radical-molecule reactivity, ozonolysis, mass spectrometry
 
      
          Hyung Kim
Focus areas: Theoretical and computational chemistry, equilibrium and nonequilibrium statistical mechanics, computer simulations, chemical reactions and spectroscopy in solution, green solvents, supercapacitors, multi-domain proteins
 
      
          Ryan Sullivan
Focus areas: Atmospheric chemistry, aerosol instrumentation, single-particle analysis, mass spectrometry, laser spectroscopy, heterogeneous chemistry, combustion, particle hygroscopicity, cloud nucleation, aerosol-cloud-climate interactions
Computational Finance
Our faculty advance the math behind modern finance to model market uncertainty and optimize decisions with AI engineering. Their leading-edge work builds more resilient systems that help industries manage risk and plan for the future.
 
      
          Dmitry Kramkov
Focus areas: Mathematical Finance and Theory of Stochastic Processes with equilibrium-based models
 
      
          Martin Larsson
Focus areas: Mathematical Finance and related topics in stochastic analysis and probability
 
      
          Mykhaylo Shkolnikov
Focus areas: Mathematical Finance, mathematical physics, and neuroscience using tools from stochastic analysis and PDE/SPDE
Cosmology & Astronomy
MCS researchers are solving the complex puzzles of the Universe — investigating dark matter, building novel telescopes and studying particles from the Big Bang to deepen our understanding of space, time and the fundamental forces that govern them.
 
      
          John Alison
Focus areas: Theory of fundamental particles and their interactions
 
      
          Rupert Croft
Focus areas: Cosmology, the Big Bang, inflation, dark matter
 
      
          Tiziana Di Matteo
Focus areas: Black holes, high-energy astrophysics, cosmology
 
      
          Tina Kahniashvili
Focus areas: High-quality cosmological data, observations of the cosmic microwave background, large-scale structure distribution, gravitational lensing and other observational data supporting a consistent "standard" model of the Universe
 
      
          Rachel Mandelbaum
Focus areas: Observational cosmology and galaxy studies, weak gravitational lensing and other analysis techniques
 
      
          Diana Parno
Focus areas: Physics of the neutrino, a fundamental particle that is generated in particle decays and nuclear reactions, which, in the Standard Model of particle physics, interacts only via the weak force
 
      
          Manfred Paulini
Focus areas: Particle physics and cosmology
 
      
          Riccardo Penco
Focus areas: Physical systems, cosmology, astrophysics, condensed matter
 
      
          Jeffrey Peterson
Focus areas: Designing and building novel radio telescopes to study dark energy
 
      
          Ira Rothstein
Focus areas: Elementary particle physics, gravity wave physics, astrophysics/cosmology and QCD
 
      
          Hy Trac
Focus areas: Computational and theoretical cosmology, astrophysics
 
      
          Matthew Walker
Focus areas: Astrophysical properties of dark matter
Life Sciences Breakthroughs
Breakthroughs in the life sciences at MCS are driving discoveries in cancer, neurodegeneration, genetic disorders and other diseases. Expert faculty are reprogramming cells, decoding genetic variations and applying chemistry and computation to transform medicine and biotechnology.
 
      
          Dannie Durand
Focus areas: Computational analysis of molecular sequence data in genetics
 
      
          Charles Ettensohn
Focus areas: Genetic encoding, early patterning, morphogenesis and development
 
      
          N. Luisa Hiller
Focus areas: Applying bacterial infections, comparative genomics, bioinformatics and phylogenetics to banked bacterial isolates from clinical infections
 
      
          Frederick Lanni
Focus areas: Mechanical activities of non-muscle cells drive many processes in embryonic development, tissue maintenance and healing, immune cell migration and function, neuronal circuit formation and progression of certain diseases
 
      
          Tina Lee
Focus areas: The structure and function relationship of the endoplasmic reticulum and how the structure of the organelle might be modified to respond to changes in cell physiology
 
      
          Adam Linstedt
Focus areas: Molecular mechanisms that establish and maintain the membrane-bounded subcellular compartments of the secretory and endocytic pathways
 
      
          Brooke McCartney
Focus areas: Cancer cell research, tumor suppression, gene mutation
 
      
          Joel McManus
Focus areas: Variation in gene expression and how it contributes to phenotypic diversity and disease
 
      
          Jonathan Minden
Focus areas: Gene and cellular mutation and pattern formation in environmental changes and proteomics
 
      
          Gordon Rule
Focus areas: Inter-molecular interactions in biological systems, enzyme-substrate interactions, protein-lipid interactions, antibody-antigen interactions, RNA structure, protein-nucleic acid interactions
 
      
          Russell Schwartz
Focus areas: Analysis of genetic variations, with specific application to inference of population subgroups and phylogenetics
 
      
          John Woolford
Focus areas: Assembly of ribosomes in eukaryotes, identify and characterize proteins necessary for the biogenesis of ribosomes
 
      
          Huaiying Zhang
Focus areas: Investigate functional significance of phase transition in cells, engineer synthetic organelles and control phase transition for cancer therapy
 
      
          Yongxin (Leon) Zhao
Focus areas: Mapping structural and molecular properties of complex biological systems
 
      
          Subha Das
Focus areas: Organic synthesis, nucleic acids chemistry, RNA biochemistry, RNA-protein recognition, nanotechnology
 
      
          Yisong (Alex) Guo
Focus areas: Spectroscopy, bioinorganic chemistry, Mössbauer and EPR spectroscopy, synchrotron radiation techniques, nuclear resonance vibrational spectroscopy (NRVS), synchrotron Mössbauer, metalloproteins, enzyme mechanisms, transition metal complexes, electronic structures, density functional theory
 
      
          Michael Hendrich
Focus areas: Spectroscopy, biophysical chemistry, enzymatic mechanisms, bioinorganic chemistry, metalloenzymes
 
      
          Anna Kietrys
Focus areas: Chemical biology, RNA structure and function, epitranscriptomics, RNA signaling, aging and neurodegeneration
 
      
          Maria Kurnikova
Focus areas: Theory, computational chemistry, biophysical, molecular modeling, continuum electrostatics, drift-diffusion models, ion channels, membrane receptors, signal transduction, membrane protein structure-function relations, flexibility and rigidity in protein dynamics
 
      
          Danith Ly
Focus areas: Bioorganic chemistry, chemical biology, gene regulation, cellular delivery, protein engineering, molecular self-assembly
 
      
          Markus Deserno
Focus areas: Theoretical and computational techniques regarding lipid membranes, proteins, viruses or DNA
 
      
          Frank Heinrich
Focus areas: Disease-relevant proteins, peptides and small molecules at interfaces and, in particular, interacting with lipid membranes
Quantum Information
Quantum science research at MCS explores particle behavior, new materials and the mysterious rules that govern matter at the smallest scales. Our expert faculty in quantum materials and particle physics are laying the groundwork for breakthroughs in computing, energy and next-generation technologies.
 
      
          Roy Briere
Focus areas: High-energy particle physics, the study of the decays and other properties of the different types of quarks
 
      
          Randall Feenstra
Focus areas: Structural and electronic properties of semiconductor materials and devices
 
      
          Benjamin Hunt
Focus areas: Condensed-matter physics, electrons’ behavior under extreme conditions in ultra-low temperatures and high magnetic fields
 
      
          Jyoti Katoch
Focus areas: Electronic, optical and spin-dependent properties of novel quantum materials like two-dimensional materials and their devices
 
      
          Curtis Meyer
Focus areas: Protons and neutrons, quarks and gluons, quantum chromodynamics
 
      
          Colin Morningstar
Focus areas: Nonperturbative phenomena in quantum field theories, with particular emphasis on the study of hadron formation and confinement in quantum chromodynamics, using computer simulations of quarks and gluons
 
      
          Jeffrey Peterson
Focus areas: Designing and building novel radio telescopes to study dark energy
 
      
          Simranjeet Singh
Focus areas: Magnetism, spin transport and spin dynamics in low-dimensional condensed matter systems
Materials of the Future
MCS researchers are advancing materials science through breakthroughs in nanomaterials, polymers and computational materials discovery. Our work in sustainable materials, machine learning for materials design and green chemistry is reshaping energy storage, biomedicine and next-generation electronics.
 
      
          Bruce Armitage
Focus areas: Bioorganic chemistry, fluorescent dyes, DNA nanotechnology, molecular evolution, peptide nucleic acids, molecular recognition of DNA/RNA, G quadruplexes
 
      
          Mark Bier
Focus areas: Biophysical chemistry, environmental chemistry, analytical chemistry, virus particles, nanoparticles, heavy ion mass spectrometry, membrane inlet mass spectrometry for environmental water analysis
 
      
          Emile Bominaar
Focus areas: Electronic structure; spin; transition-metal complexes; metal clusters; theory; computational; density functional theory; exchange interactions; hyperfine interactions; Mössbauer spectroscopy; magneto optical spectroscopy; magneto chemistry; bioinorganic chemistry
 
      
          Roberto Gil
Focus areas: Nuclear magnetic resonance spectroscopy, residual dipolar couplings, residual chemical shift anisotropy, anisotropic polymer gels, natural products, characterization of nucleic acids, peptides, synthetic polymers, small molecules in general
 
      
          Olexandr Isayev
Focus areas: Theoretical and computational chemistry, machine learning, cheminformatics, drug discovery, computer-aided molecular design, materials informatics
 
      
          Rongchao Jin
Focus areas: Nanoscience, nanoparticles, synthesis, catalysis, optics
 
      
          Tomasz Kowalewski
Focus areas: Physical chemistry, atomic force microscopy, proximal probe techniques, organic electronics, nano-structured materials, nanographene, self-assembly of organic materials, characterization of nanostructures, device fabrication and characterization
 
      
          Krzysztof Matyjaszewski
Focus areas: Polymer synthesis, controlled/living polymerization, macromolecular engineering, bio-related polymers, organic/inorganic hybrids, catalysis, green chemistry
 
      
          Kevin Noonan
Focus areas: Polymer chemistry, organometallics, homogeneous catalysis, organophosphorus chemistry
 
      
          Linda Peteanu
Focus areas: Photophysics, laser spectroscopy, microscopy, Stark spectroscopy, conjugated materials, nucleic acids, fluorescent labels, plasmonics
 
      
          Stefanie Sydlik
Focus areas: Polymer science, materials chemistry, biomaterials, electronic materials
 
      
          Newell Washburn
Focus areas: Materials chemistry, biomaterials, green chemistry, machine learning
 
      
          David Yaron
Focus areas: Theory, computational, electronic structure theory, machine learning, materials theory, photophysics, spectroscopy
 
      
          Sara Majetich
Focus areas: Magnetic nanoparticles that have very uniform sizes, their fundamental behavior and possible applications in data storage media, permanent magnets and biomedicine
 
      
          Michael Widom
Focus areas: Theoretical modeling of novel materials in condensed matter and biological physics settings, methods of statistical mechanics, quantum mechanics and computer simulation used to investigate structure, stability and properties of these materials
 
      
          Irene Fonseca
Focus areas: Mathematical study of shape memory alloys, ferroelectric, magnetic materials, composites, thin structures, phase transitions in fluids and solids and the mathematical analysis of image segmentation, denoising, detexturing and recolorization in computer vision
 
      
          Giovanni Leoni
Focus areas: Variational problems involving material defects, such as dislocations; the epitaxial growth of a thin film over a crystalline substrate; phase field models for anisotropic crystalline energies; phase transitions problems; water waves
Neuroscience
MCS neuroscience research is decoding how neural circuits drive behavior, movement and decision-making. Their work reveals how experience, injury and disease reshape the brain, which is advancing treatments for conditions like Parkinson’s disease, dystonia and stroke.
 
      
          Alison Barth
Focus areas: Understanding how experience assembles and alters the properties of neural circuits in the cerebral cortex in both normal and disease states
 
      
          Aryn Gittis
Focus areas: Neural circuits in the basal ganglia in movement disorders such as Parkinson’s disease and dystonia
 
      
          Kate Hong
Focus areas: Determine how cortical and subcortical activity cooperate to mediate sensory-motor transformations in parallel, providing a foundation for understanding behavioral deficits and recovery mechanisms associated with cortical injury
 
      
          Eric Yttri
Focus areas: Establish how neural circuits lead to action selection decisions in impairments like stroke and Parkinson's disease
Mathematical Foundations of Artificial Intelligence
MCS researchers are building the mathematical frameworks that power AI — advancing combinatorics, probability, logic and analysis to create stronger algorithms, optimize computation and tackle high-dimensional problems in data science and machine learning.
 
      
          Tom Bohman
Focus areas: Extremal and probabilistic combinatorics and discrete mathematical problems
 
      
          Boris Bukh
Focus areas: Combinatorial objects
 
      
          Clinton Conley
Focus areas: Descriptive set theory, equivalence relations arising from measurable group actions or measurable graphs
 
      
          James Cummings
Focus areas: Combinatorial objects, structure theory of linear orderings and posets, rainbow Ramsey theory, strong forcing axioms, new forcing techniques for obtaining consistency results in singular cardinal combinatorics
 
      
          Florian Frick
Focus areas: Geometric-topological methods, intersection combinatorics of convex hulls in Euclidean space, inscribing geometric shapes into curves, partitioning a point set by hyperplanes
 
      
          Alan Frieze
Focus areas: Probabilistic Combinatorics and its application to Theoretical Computer Science and Operations Research
 
      
          Rami Grossberg
Focus areas: Model theory of mathematical logic, related combinatorial, set-theoretic problems and applications to algebra
 
      
          Gautam Iyer
Focus areas: Studies partial differential equations arising in applied mathematics
 
      
          David Kinderlehrer
Focus areas: Applied mathematics and analysis of differential equations in materials, cell biology, mechanisms of intracellular transport and models of ion transport
 
      
          Po-Shen Loh
Focus areas: Combinatorics, probability, computer science
 
      
          Wesley Pegden
Focus areas: Probabilistic combinatorics, combinatorial game theory, graph theory, discrete geometry
 
      
          Agoston Pisztora
Focus areas: Probabilistic analysis of random fields, certain disordered systems and phase transitions
 
      
          Ernest Schimmerling
Focus areas: Set theory, hierarchy of large cardinal axioms
 
      
          Dejan Slepčev
Focus areas: Applied analysis, partial differential equations, calculus of variations, optimal transportation, as well as tools of probability, statistics, functional analysis and scientific computation to address applied problems
 
      
          Richard Statman
Focus areas: Mathematical logic, proof theory and the theory of computation, theory of programming languages (computer science), theory of functional programming, lambda calculus/combinatory logic
 
      
          Tomasz Tkocz
Focus areas: Analysis, probability and convex geometry, with an emphasis on high-dimensional phenomena, inequalities in information theory
 
      
          Noel Walkington
Focus areas: The development and analysis of numerical algorithms required for the approximation of partial differential equations
Latest in MCS Research
 
      
      Create the Future With Us
Research at MCS isn’t about observation — it’s about invention. Here, you will collaborate and contribute to the discoveries that will change the world.
 
      
     
      
     
      
     
      
    