We have two Bruker 500 MHz NMR spectrometers. One is a brand new NEO with a Multinuclear Prodigy Cryoprobe and the other an AVANCE III with a Multinuclear BBFO PLUS SMART room temperature probe. We can perform Multinuclear and Multidimensional NMR Experiments in both Direct and Inverse Detection Mode using Gradient-Assisted Spectroscopy (GRASP). (Funded in part by NSF grant # CHE-9808188, CHE-1039870 and CHE-1726525 )
Our Facility is capable of performing a wide variety of NMR experiment. Some of the most common experiments are listed below by category.
Routine 1D NMR Spectroscopy
- Standard 1H, 13C, 31P, 19F, 15N, 29Si NMR experiments
Dynamic NMR Spectroscopy
- High and Low Temperature Experiments
- Saturation Transfer Experiments
- EXSY (EXchange SpectroscopY)
1D Multipulse Sequences
- Measurement of the Spin-Lattice Relaxation Time T1
- Measurement of the Spin-Spin Relaxation Time T2
- 13C DEPT- 45, 90 and135
- Water Suppression by Presaturation
Multinuclear Multidimensional NMR Spectroscopy
- 2D Homonuclear Correlation Experiments: COSY-Experiment and its variants, NOESY, ROESY, TOCSY.
- 2D Heteronuclear Correlation Experiments: HSQC, HMBC, HSQC-TOCSY.
NMR Spectroscopy with Pulsed Field Gradients
- Measurement of Diffusion Constant using the Pulsed Gradient Spin-Echo Experiment (DOSY)
- WATERGATE (water suppression experiment)
- Water Suppression by Excitation Sculpting
- Plus all the Gradient-Selected Multidimensional Experiments