Carnegie Mellon University

Cell & Tissue Engineering

Research in Cell & Tissue Engineering at Carnegie Mellon encompasses the mechanical events of single cells, multicellular systems, and subcellular structures.

Three main focus areas within Cell & Tissue Engineering include Cellular Mechano-Sensing & Actuation, Mechanics of Biomolecular Structures, and Tissue Engineering and Regenerative Medicine.

Some projects apply engineering approaches to understand mechanical properties of the cell, while other projects reveal mechanical properties critical for applications like tissue engineering. Faculty members interact extensively with those in areas of computation, image processing, modeling, materials, microfabrication, and microfluidics to apply a rich set of research tools to cell and tissue level biomedical problems.

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Rosalyn Abbott

Assistant Professor, Biomedical Engineering

Research Interests

Cell & tissue engineering; biomaterials; adipose microenvironments; disease modeling; tissue regeneration

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Bruce A. Armitage

Professor of Chemistry, Biological Sciences, and Biomedical Engineering

Research Interests

Gene regulation; nucleic acid nanotechnology; fluorescence imaging

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Christopher J. Bettinger

Associate Professor, Biomedical Engineering and Materials Science & Engineering

Research Interests

BioMEMS for tissue regeneration; biodegradable electronic devices; biomimetic tissue-device interfaces; biomaterials synthesis; microfabrication of biomaterials 

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Marcel P. Bruchez

Professor, Chemistry, Biological Sciences, and Biomedical Engineering

Research Interests

Fluorescent probes for cell imaging; luminescent nanocrystal probes

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Phil G. Campbell

Research Professor, Biomedical Engineering, Engineering Research Accelerator, Biological Sciences, and Materials Science & Engineering

Research Interests

Bioavailability and proteolytic processing of growth factors; musculoskeletal tissue repair and regeneration; biomimetic tissue engineering materials

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Kris N. Dahl

Associate Professor, Chemical Engineering, Biomedical Engineering, and Materials Science & Engineering

Research Interests

Mechanics of the cell nucleus in normal and disease states; nuclear mechanics in stem cell differentiation and cancer progression; mechanotransduction; cellular interactions with nanomaterials

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Michael M. Domach

Professor, Chemical Engineering and Biomedical Engineering

Research Interests

High throughput systems for cell growth analysis; optimization of bioreactor performance

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Adam W. Feinberg

Associate Professor, Biomedical Engineering and Materials Science & Engineering

Research Interests

Tissue regeneration in neuromuscular and cardiovascular systems; self-assembly and multi-scale coupling in biological systems; cell-material interactions; protein-based materials; bioprosthetics; stem cell differentiation and engineered morphogenesis

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Mathias Loesche

Professor, Physics and Biomedical Engineering

Research Interests

Biomaterials; bionanotechnology; structural biology; membrane protein complexes

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Carmel Majidi

Associate Professor, Mechanical Engineering, Biomedical Engineering, Robotics Institute, and Civil and Environmental Engineering

Research Interests

Elastically soft sensors and circuits; soft multifunctional materials; soft lithography fabrication

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Michael E. McHenry

Professor, Materials Science & Engineering and Biomedical Engineering

Research Interests

Magnetic nanoparticles for tagging cells and MRI enhancement; cellular interactions with nanocrystalline magnetic materials; cellular effects of RF heating of magnetic nanoparticles; applications of magnetic nanoparticles and ferrogels in tissue engineering

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Stefanie A. Sydlik

Assistant Professor, Chemistry and Biomedical Engineering

Research Interests

Materials chemistry; graphene; stem cells; tissue regeneration; cell-instructive material

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Robert D. Tilton

Professor, Biomedical Engineering and Chemical Engineering

Research Interests

Nanoparticle probes; nanoparticle-cell interactions; environmental effects of nanoparticles; surfactant-based carriers for pulmonary drug delivery; protein adsorption and protein drug delivery; cell sorting technologies

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Yu-li Wang

Mehrabian Professor, Biomedical Engineering

Research Interests

Mechanical interactions between cells and the environment; mechanisms of cell migration and division; cellular mechanical activities; synthetic polymeric materials for cell, tissue, and organ engineering

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Newell R. Washburn

Associate Professor, Biomedical Engineering, Chemistry, and Materials Science & Engineering

Research Interests

Materials chemistry; biomaterials; green chemistry; machine learning

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Victoria Webster-Wood

Assistant Professor, Mechanical Engineering and Biomedical Engineering

Research Interests

Bioinspired robotics; biohybrid robotics; cell & tissue engineering; biomaterials; organic actuators; organic control

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Kathryn A. Whitehead

Assistant Professor, Chemical Engineering and Biomedical Engineering

Research Interests

Drug delivery; personalized medicine; bionanotechnology