Carnegie Mellon University
College of Engineering  ›  Biomedical Engineering  ›  People  ›  Faculty  ›  profile  ›  Keith E. Cook

Keith Cook

Dr. Keith E. Cook

The David Edward Schramm Professor and Head, Biomedical Engineering

Address
Scott Hall 4N120A
Carnegie Mellon University
5000 Forbes Avenue
Pittsburgh, PA 15213

Education

  • B.S.E., Mechanical Engineering, University of Michigan, 1993
  • B.S.E., Engineering Science, University of Michigan, 1993
  • M.S., Biomedical Engineering, Northwestern University, 1996
  • Ph.D., Biomedical Engineering, Northwestern University, 2000

Bio

Dr. Keith Cook is the David Edward Schramm Professor and Head at Carnegie Mellon University (CMU) in its Department of Biomedical Engineering. Prior to his appointment at CMU, Dr. Cook was a Research Associate Professor in Biomedical Engineering and in Surgery at the University of Michigan. It was at the University of Michigan where Dr. Cook obtained his BSE in both Mechanical Engineering and Engineering Science. He received his MS and Ph.D. in Biomedical Engineering from Northwestern University.

Dr. Cook’s research interests include:

  • Advanced Respiratory Support: Design and development of artificial lungs, liquid ventilation hardware and techniques, and animal models of lung disease
  • Blood-Biomaterial Interactions: Development of biomaterials offering endothelial-like properties to increase the longevity of blood processing artificial organs
  • Pulmonary Drug Delivery: Development of perfluorocarbon emulsions for intra-pulmonary drug delivery to treat lung disease
  • Right Ventricular Function: Mathematical modeling of right ventricular function to better understand dysfunction under stressed states, such as high afterload and hypoxia

Dr. Cook is a member of the American Society of Artificial Internal Organs and the Biomedical Engineering Society. He is on the Editorial Board for the American Society of Artificial Internal Organs (ASAIO) Journal. In addition, Dr. Cook is a reviewer for numerous publications, including but not limited to, Biotechnology and Bioengineering, Annals of Biomedical Engineering, and Critical Care Medicine.

Research

Keith Cook's research focuses on applying engineering to critical care medicine. This research melds mechanical, chemical, and material science concepts toward the development of artificial and tissue-based lungs, pulmonary drug delivery, and the computational modeling and prevention of coagulation in medical devices.
Current research projects in his group include thoracic artificial lungs, biofabricated tissue-based lungs, new biomaterial approaches for reducing coagulation at artificial surfaces, and perfluorocarbon emulsions for pulmonary drug delivery. Of note, his laboratory was the first to produce 24-hour, one-week, and 30-day in vivo studies of thoracic artificial lungs, and his group is working on an artificial lung intended as destination therapy for years of respiratory support. Professor Cook currently serves as the Faculty Director of the Bioengineered Organs Initiative at CMU and is a fellow of the American Institute for Medical and Biological Engineering.

Research Interests: artificial lungs; hemodynamics; pulmonary drug delivery; liquid ventilation; right ventricular function; critical care medicine

  

Awards and Recognition

  • Fellows, American Institute for Medical and Biological Engineering (AIMBE), 2018

  • Section Editor, American Society for Artificial Internal Organs (ASAIO) Journal, 2007-present

  • University of Michigan Research Faculty Recognition Award, 2011

 

  • Michigan Society for Medical Research Bennett J. Cohen Education Leadership Award, 2011
  • Top Abstract, American Society of Artificial Internal Organs, 2009
  • Top Abstract, Respiratory Section, American Society of Artificial Internal Organs, 2008

Media Reports