Carnegie Mellon University

En Cai

Assistant Professor

625B Mellon Institute
Department of Biological Sciences
Carnegie Mellon University
4400 Fifth Avenue
Pittsburgh, PA 15213

Lab website


En Cai


Ph.D., Univerity of Illinois at Urbana-Champaign
Postdoctoral Appointment, Univerity of Illinois at Urbana-Champaign
Postdoctoral Appointment, University of California, San Francisco


Megan K Ruhland, Edward W Roberts, En Cai, Adriana M Mujal, Kyle Marchuk, Casey Beppler, David Nam, Nina K Serwas, Mikhail Binnewies and Matthew F Krummel. Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells. Cancer Cell, 37, 786-799, 2020

En Cai, Kyle Marchuk, Peter Beemiller, Casey Beppler, Matthew G Rubashkin, Valerie M Weaver, Audrey G ́erard, Tsung-Li Liu, Bi-Chang Chen, Eric Betzig, Frederic Bartumeus and Matthew F Krummel. Visualizing dynamic microvillar search and stabilization during ligand detection by T cells. Science, 356, eaal3118, 2017

Sang Hak Lee, Chaoyi Jin, En Cai, Pinghua Ge, Yuji Ishitsuka, Kai Wen Teng, Andre A. de Thomaz, Duncan Nall, Murat Baday, Okunola Jeyifous, Daniel Demonte, Christopher M. Dundas, Sheldon Park, William N. Green, Paul R. Selvin. Super-resolution imaging of synaptic and extra-synaptic pools of AMPA receptors with different-sized fluorescent probes. eLife, 6:e27744, 2017

Yong Wang, En Cai, Tobias Rosenkranz, Pinghua Ge, Kai Wen Teng, Hee Jung Chung, Fred- erick Sachs, William N. Green, Philip Gottlieb, and Paul R. Selvin. Small quantum dots conju- gated to nanobodies as immunofluorescence probes for nanometric microscopy. Bioconjugate Chemistry, Dec 17;25(12):2205-11, 2014.

En Ca, Pinghua Ge, Sang Hak Lee, Okunola Jeyifous, Yong Wang, Yanxin Liu, Katie M. Wilson, Sung Jun Lim, Michele A. Baird, John E. Stone, Kwan Young Lee, Michael W. Davidson, Hee Jung Chung, Klaus Schulten, Andrew M. Smith, William N. Green, Paul R. Selvin. Stable small quantum dots for synaptic receptor tracking on live neurons. Angewandte Chemie International Edition, 53:12484-12488, 2014.

Yong Wang, En Cai, Janet Sheung, Sang Hak Lee, Kai Wen Teng, and Paul R. Selvin. Fluorescence imaging with one-nanometer accuracy (FIONA). Journal of Visualized Ex- periments (JoVE), 91:e51774, 2014.

Yong Wang, Gilbert Fruhwirth, En Cai, Tony Ng, and Paul R. Selvin. 3D super-resolution imaging with blinking quantum dots. Nano Lettters, 13:5233-5241, 2013.

Sang Hak Lee, Murat Baday, Marco Tjioe, Paul D. Simonson, Ruobing Zhang, En Cai, and Paul R. Selvin. Using fixed fiduciary markers for stage drift correction. Optics Express, 20:12177-12183, 2012.

Ning Wu, R. F. Sabirianov, Chun-gang Duan, W. N. Mei, David Wisbey, Ya. B. Losovyj, M. Manno, C. Leighton, En Cai, Jiandi Zhang, and Peter A. Dowben. The surface stability of CoS2(100). Journal of Physics-Condensed Matter, 20:215231, 2008.

Ya. B. Losovyi, Melanie Klinke, En Cai, Idaykis Rodriguez, Jiandi Zhang, L. Makinistian, A. G. Petukhov, E. A. Albanesi, P. Galiy, Ya. Fiyala, Jing Liu, and Peter. A. Dowben. The elec- tronic structure of surface chains in the layered semiconductor In4Se3(100). Applied Physics Letters, 92:122107, 2008.