The research centers affiliated with the Mellon College of Science enhance the environment for creative work within and across disciplines.
- Art Conservation Research Center
- Bruce and Astrid McWilliams Center for Cosmology
- Center for Atmospheric Particle Studies
- Center for Computational Finance
- Center for Macromolecular Engineering
- Center for Nano-enabled Device and Energy Technologies (CNXT) (joint with CIT)
- Center for the Neural Basis of Cognition
- Center for Nonlinear Analysis
- Center For Nucleic Acids Science And Technology (CNAST)
- Institute for Green Oxidation Chemistry
- Molecular Biosensor & Imaging Center
- Pittsburgh NMR Center for Biomedical Research
- Pittsburgh Supercomputing Center
- Ray and Stephanie Lane Center for Computational Biology