Carnegie Mellon University

Zheng Lab

Micro & Nano Integrated Biosystem Laboratory (MINIBio)

The Zheng MINIBio Lab aims at developing and applying micro/nano technologies for biological and medical applications. On one hand, we are interested in studying miniaturized devices and systems that can be integrated with biological system in vitro and in vivo. On the other hand, we are eager to apply these technologies for fundamental biological research and clinic diagnosis and treatment. The research is highly multidisciplinary, interfacing at engineering, biological sciences, physical sciences, and medicine. Current research focuses of the group include:

• Micro/nano materials, devices and systems for liquid biopsy-based cancer diagnosis, including enrichment and analysis of circulating tumor cells (CTCs) and extracelluar vesicles (EVs).
• Nanomaterials and nanomaterial integrated microdevices for infectious disease diagnosis and pathogen discovery.
• Nanomaterials and implantable devices for drug delivery and disease monitoring.
• Nanomaterials for proteomics including peptide capture and ultrafast protein digestion.
• Lab-on-chip biomarker detection in body fluid.