Carnegie Mellon University

Abbott Lab

Departments of Biomedical Engineering and Materials Science and Engineering

The Abbott lab at Carnegie Mellon University works at the interface of materials science and regenerative medicine. We investigate how the 3D microenvironment affects tissue development and disease. Our current research focuses on adipose tissue engineering strategies, silk biomaterials and non-invasive tissue assessments to study obesity and it's link to type II diabetes. For more information about what we do, check out our current research projects, publications, and outreach events. To join our team please contact us!

Professor Abbott is featured on "My Future Tech Podcast!" Check it out!  

Recent updates

7/2021 - The lab's work on the use of non-invasive, therapeutic ultrasound to trigger and adjust silk scaffold degradation post-implantation is featured in a news article about Professor Abbott.

7/2021 - Megan's paper on silk as a green biomaterial is out!

6/2021 - Dakshi's paper exploring the biophysical influences of silk biomaterials on directing cellular behaviors (materbiology!) is published.

6/2021 - We are grateful to have received the Samuel and Emma Winters Foundation Award for our work towards synthesizing biomimetic mosquito inspired painless polymeric microneedles to enable pulsatile insulin release. Dakshi will get started on this project when she joins us in the US later this summer!

6/2021 - Check out our preprint for the fat in the lung work! In collaboration with the Ren group, we show that a decellularized lung matrix can be repurposed for creating a vascularized adipose tissue graft!

5/2021 - Congratulations to Megan for being selected for a Swartz Center for Entrepreneurship Innovation Fellowship! Through the fellowship she will work with Professor Abbott on clinically translating her technique for degrading silk biomaterials non-invasively to improve regeneration (patent pending!) in their company Biombyx, LLC!

Check out more recent events in the group

Recent Publications

DeBari MK, Ng WH, Griffin MD, Kokai LE, Marra KG, Rubin JP, Ren X, Abbott RD. Engineering a 3D Vascularized Adipose Tissue Construct using a Decellularized Lung Matrix. Biomimetics. 2021, 6(3), 52.

DeBari MK, King C, Altgold TA, Abbott RD. Silk Fibroin as a Green Material. ACS Biomater Sci Eng. 2021 Jul 14.

Kochhar D, DeBari MK, Abbott RD. The Materiobiology of Silk: Exploring the Biophysical Influence of Silk Biomaterials on Directing Cellular Behaviors. Front Bioeng Biotechnol. 2021;9:697981.

DeBari MK, Niu X, Scott JV, Griffin M, Pereira SR, Cook KE, He B, Abbott RD. Therapeutic Ultrasound Triggered Silk Fibroin Scaffold Degradation. Adv Healthc Mater. 2021 Mar.

Abbott RD, LeBlanc S, Melville MC, Moore S, Zapanta CM. Work in progress: Incorporating interactive modules related to cell culture and plasmid design into introduction to biomedical engineering. American Society of Engineering Education. June 2020.

DeBari MK, Abbott RD. Adipose Tissue Fibrosis: Mechanisms, Models, and Importance. International Journal of Molecular Sciences. 2020 Aug; 21(17).

Check out more publications from the group...