Carnegie Mellon University
Abbott Lab

Departments of Biomedical Engineering and Materials Science and Engineering

The Abbott lab at Carnegie Mellon University works at the interface of materials science and regenerative medicine. We investigate how the 3D microenvironment affects tissue development and disease. Our current research focuses on adipose tissue engineering strategies, silk biomaterials and non-invasive tissue assessments to study obesity and it's link to type II diabetes. For more information about what we do, check out our current research projects, publications, and outreach events. To join our team please contact us!

 


Professor Abbott is featured on "My Future Tech Podcast!" 

Recent updates

1/2026 Lindsey gives a talk at the Gordon Research Conference "Foods of the Future" on our 3D printing fat work for cultivated meat applications.

1/2026 Prof. Abbott gives a talk at the Hillman Cancer Center "Cancer Biology Program Seminar Series" on our fat and liver in vitro models.

11/2025 Prof. Abbott gives a talk titled "A Consumer-Centric Approach: Designing Cultivated Meat for Taste, Texture, and Health” at the Japan Association for Cellular Agriculture (JACA) Science, Regulation, and Communication Symposium titled: A Three-Wheel Dialogue for Cultivated-Food-Ready Futures. The event was hosted at the University of Tokyo.

10/2025  Nate presents his work on "Silk Scaffolds as a Model Biomaterial for Investigating the Mechanisms of Benign Prostatic Hyperplasia" at the Pittsburgh Center for Training in Kidney, Urology and Hematology Research Seminar.

10/2025 Nikita presents a poster on "Sex-Related Differences in Young and Old BALB/c Responses to Implanted Silk Fibroin Scaffolds" at the Biomedical Engineering Society Annual Meeting in San Diego.

9/2025 Prof. Abbott was invited to present on "3D Printing High Lipid Content Tissues" at the International Federation for Adipose Therapeutics and Science (IFATS) conference. The lab was well-represented by Lindsey and Khushi, who both delivered impressive talks on their research. A special congratulations to Lindsey, who received the Best Presentation Award!

 Check out more recent events in the group

Recent Publications

Johnston EK, Dassau T, Muraskin NA, Abbott RD. Automated adipocyte and lipid tracer for immunohistochemistry images. Sci Rep. 2025 Feb 7;15(1):4643.

Huff LK, Amurgis CM, Kokai LE, Abbott RD. Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery. Front Bioeng Biotechnol. 2024 Jun 25:12:1404327.

Huff LK, Ling Z, DeBari MK, Ren X, Abbott RD. “Repurposing Decellularized Lungs to Generate Vascularized Fat.” Adipose-Derived Stem Cells Methods and Protocols. 3rd edition. Edited by Jeffrey Gimble, Bruce Bunnell, Cecilia Sanchez, and Trivia Frazier. Lab protocol Series - Methods in Molecular Biology, published by Springer Nature 2024.

Dewal RS, Yang FT, Baer LA, Vidal P, Hernandez-Saavedra D, Seculov NP, Ghosh A, Noé F, Togliatti O, Hughes L, DeBari MK, West MD, Soroko R, Sternberg H, Malik NN, Puchulu-Campanella E, Wang H, Yan P, Wolfrum C, Abbott RD, Stanford KI. Transplantation of Committed Pre-adipocytes from Brown Adipose Tissue improves Whole-body Glucose Homeostasis. iScience. 2024 Jan 17.

DeBari MK, Johnston EK, Griffin MD, Scott JV, Ilzuka E, Sun W, Webster-Wood VA, Abbott RD. A Preliminary Study on Factors That Drive Patient Variability in Human Subcutaneous Adipose Tissues. Cells 2024, 13(15), 1240.

Check out more publications from the group...