Biological Physics
Supramolecular Structures Lab
Lösche/Heinrich Group
Mathias Lösche
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Contact412-268-2735, |
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Education
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| 1976 – 83 | Undergraduate School in Physics (Ulm Univ., Germany), M.S. 1983 |
| 1983 – 86 | Graduate Program in Biophysics (TU Munich, Germany), Ph.D. 1986 |
| 1986 – 88 | Postdoctoral Researcher in Biophysics (UC San Diego, CA) |
| 1988 – 94 | Asst. Professor in Phys. Chem. (Univ. Mainz, Germany), Habilitation 1994 |
| 1995 | Professorship (tenure) in Exp. Physics (Leipzig University, Germany) |
Professional Appointments
| 2008 – | Professor of Biomedical Engineering (by courtesy), Carnegie Mellon |
| 2005 – | Professor of Physics, Carnegie Mellon, Physics Dept., Pittsburgh, PA |
| 2002 – 06 | Director, CNBT Consortium, NIST Cntr. f. Neutr. Res., Gaithersburg, MD |
| 2002 – 05 | Res. Professor, Dept. of Biophysics, Johns Hopkins, Baltimore, MD |
| 1998 – 02 | Head, Biomembrane Physics Group, Leipzig University, Germany |
| 1994 – 05 | Assoc. Prof. of Physics, Exp. Phys., Leipzig University, Germany |
| 1988 – 94 | Assistant Professor in Physical Chemistry, Mainz University, Germany |
| 1986 – 88 | Post-doctoral research fellow, Biophysics Dept, UCSD, La Jolla, CA |
Recent Publications
P. Cizas, R. Budvytyte, R. Morkuniene, R. Moldovan, M. Broccio, M. Lösche, G. Niaura, G. Valincius, and V. Borutaite, Size-dependent neurotoxicity of β-amyloid oligomers, Arch. Biochem. Biophys. 496 (2010), 84 - 92.
ABB Website
S. Shenoy, R. Moldovan, J. Fitzpatrick, D. J. Vanderah, M. Deserno, and M. Lösche, In-plane homogeneity and lipid dynamics in tethered Bilayer Lipid Membranes (tBLMs), Soft Matter 6 (2010), 1263 - 1274.
Soft Matter Website
M. B. Smith, D. J. McGillivray, J. Genzer, M. Lösche, and P. K. Kilpatrick, Neutron reflectometry of peptide-incorporated suported hybrid bilayers, Soft Matter 5 (2010), 862 - 865.
Soft Matter Website
S. A. Holt, A. P. Le Brun, C. F. Majkrzak, D. J. McGillivray, F. Heinrich, M. Lösche, and J. H. Lakey, An ion channel containing model membrane: Structural determination by magnetic contrast variation neutron reflectometry, Soft Matter 5 (2009), 2576 - 2586.
Soft Matter Website
F. Heinrich, T. Ng, D. J. Vanderah, P. Shekhar, M. Mihailescu, H. Nanda, and M. Lösche, A new lipid anchor for sparsely-tethered bilayer lipid membranes, Langmuir 25 (2009), 4219 - 4229.
Langmuir Website
D. J. McGillivray, G. Valincius, F. Heinrich, J. W. F. Robertson, D. J. Vanderah, W. Febo-Ayala, I. Ignatjev, M. Lösche, and J. J. Kasianowicz, Structure of functional Staphylococcus aureus α-hemolysin channels in tethered bilayer lipid membranes, Biophys. J. 96 (2009), 1547 - 1553. BJ Website
G. Valincius, F. Heinrich, R. Budvytyte, D. J. Vanderah, D. J. McGillivray, Y. Sokolov, J. E. Hall, and M. Lösche, Soluble amyloid β oligomers affect dielectric membrane properties by bilayer insertion and domain formation: Implications for cell toxicity, Biophys. J. 95 (2008), 4845 – 4861. BJ Website / download BioFast preprint / download supplement
D. J. McGillivray, G. Valincius, D. J. Vanderah, W. Febo-Ayala, J. T. Woodward, F. Heinrich, J. J. Kasianowicz, and M. Lösche, Molecular-scale structural and functional characterization of sparsely tethered bilayer membranes, Biointerphases 2 (2007), 21 – 33. download paper / download supplement
J. Pittler, W. Bu, D. Vaknin, A. Travesset, D. J. McGillivray, and M. Lösche, Charge inversion at minute electrolyte concentrations, Phys. Rev. Lett. 97 (2006), 046102.
J. A. Dura, D. J. Pierce, C. F. Majkrzak, N. Maliszewskyj, D. J. McGillivray, M. Lösche, K. V. O’Donovan, M. Michailescu, U. A. Perez-Salas, D. L. Worcester, and S. H. White, AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences, Rev. Sci. Instrum. 77 (2006), 074301.
Full list of publications
Short CV for Mathias Lösche