Intellectual Property
The Center for Macromolecular Engineering actively pursues patent protection for major developments made by its researchers and as a consequence of the proactive filing history of the ATRP Consortium and CRP Consortium twenty nine US Patents have issued. The fundamental patents have been filed, and many have issued, in other countries around the world.
Further information on the following CMU patents and patent applications on various aspects of controlled/“living” radical polymerization can be obtained at:
Issued U.S. Patents
- 5,077,078 Surface Modification of Plastic Optical Fibers; Jules B. Puschett, Krzysztof Matyjaszewski; Issued December 31, 1991, Filed March 14, 1990
- 5,138,008 Process for the production of linear polyphosphazenes Robert A. Montague, Krzysztof Matyjaszewski Issued August 11, 1992 Filed June 5, 1990
- 5,236,667 Surface Modification of Plastic Optical Fibers Jules B. Puschett, Krzysztof Matyjaszewski, Bhalchandra Karandikar; Issued August 17, 1993, Filed June 25, 1991
- 5,312,871 Free radical polymerization process, Daniela Mardare; Krzysztof A. Matyjaszewski; Issued May 17, 1994 Filed July 27, 1993.
- 5,382.644 Linear polyphosphazenes and a process for their production; Robert A. Montague, Krzysztof Matyjaszewski; Issued January 17, 1995, Filed August 10, 1992
- 5,688,888 Peralkylated phosphazene base-catalyzed silanol condensation method, Frank Steven Burkus, II; Krzysztof Matyjaszewski; (Pittsburgh, PA), Slawomir Rubinsztajn; Issued November 18, 1997, Filed April 8, 1996.
- 5,763,548 (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization, Krzysztof Matyjaszewski; Jin-Shan Wang; Issued June 9, 1998, Filed March 31, 1995.
- 5,789,487 Preparation of novel homo- and copolymers using atom transfer radical polymerization; Krzysztof Matyjaszewski, Simion Coca; Scott G. Gaynor, Yoshiki Nakagawa, Seong Mu Jo; Issued August 4, 1998, Filed July 10, 1996
- 5,807,937 Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties; Krzysztof Matyjaszewski, Simion Coca, Scott G. Gaynor, Dorota Greszta; Timothy E. Patten, Jin-Shan Wang, Jianhui Xia; Issued September 15, 1998, Filed November 15, 1995
- 5,854,364 Process for the controlled radical polymerization or copolymerization of (meth)acrylic, vinyl, vinylidene and diene monomers, and (co)polymers obtained; Thierry Senninger, Laurent Sanchez, Vincent Darcos, Dominique Lastecoueres, Jean-Baptiste Verlhac, Krzysztof Matyjaszewski, Issued December 29, 1998, Filed June 27, 1997
- 5,910,549 Method for preparation of alkoxyamines from nitroxyl radicals, Krzysztof Matyjaszewski, Dorota Greszta; Issued June 8, 1999, Filed August 22, 1996.
- 5,945,491 Preparation of novel homo- and copolymers using atom transfer radical polymerization, Krzysztof Matyjaszewski, Simion Coca; Scott G. Gaynor, Yoshiki Nakagawa, Seong Mu Jo; Issued August 31, 1999, Filed September 30, 1997
- 6,111,022 Preparation of novel homo- and copolymers using atom transfer radical polymerization, Krzysztof Matyjaszewski, Simion Coca; Scott G. Gaynor, Yoshiki Nakagawa, Seong Mu Jo, Issued August 29, 2000, Filed December 8, 1998.
- 6,121,371Application of atom transfer radical polymerization to water-borne polymerization systems, Krzysztof Matyjaszewski, Scott G. Gaynor, Jian Qiu, Mircea Teodorescu; Issued September 19, 2000, Filed July 31, 1998.
- 6,124,411 Preparation of novel Homo- and copolymers using atom transfer radical polymerization, Krzysztof Matyjaszewski, Simion Coca; Scott G. Gaynor, Yoshiki Nakagawa, Seong Mu Jo, Issued September 26, 2000, Filed September 14, 1999.
- 6,162,882 Preparation of novel homo- and copolymers using atom transfer radical polymerization, Krzysztof Matyjaszewski, Simion Coca; Scott G. Gaynor, Yoshiki Nakagawa, Seong Mu Jo, Issued December 19, 2000, Filed November 2, 1999.
- 6,288,186 Rate enhancement of nitroxyl radical-mediated polymerization, Krzysztof Matyjaszewski, Dorota Greszta; Issued September 11, 2001, Filed November 27, 1998.
- 6,407,187 (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization, Krzysztof Matyjaszewski; Jin-Shan Wang; Issued June 18, 2002, Filed March 3, 1998
- 6,512,060 Atom or group transfer radical polymerization, Krzysztof Matyjaszewski, Scott G. Gaynor, Simion Coca; Issued: January 28, 2003, Filed July 23, 1999
- 6,538,091 Atom or group transfer radical polymerization, Krzysztof Matyjaszewski, Scott G. Gaynor, Simion Coca; Issued: March 25, 2003, Filed February 4, 1998
- 6,541,580 Atom or group transfer radical polymerization, Krzysztof Matyjaszewski, Scott G. Gaynor, Simion Coca; Issued April 1, 2003, Filed August 6, 1999
- 6,624,262 Polymerization process for ionic monomers , Krzysztof Matyjaszewski; Nicolay Tsarevsky; Issued September 23, 2003, Filed October 5, 2001
- 6,624,263 (Co) polymers and a novel polymerization process based on atom (or group) transfer radical polymerization, Krzysztof Matyjaszewski, Jin-Shan Wang; Issued September 23, 2003, Filed March 13, 2002.
- 6,627,314 (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization, Krzysztof Matyjaszewski; Jin-Shan Wang; Issued: September 23, 2003, Filed March 13, 2002
- 6,759,491 Simultaneous reverse and normal initiation of ATRP, Krzysztof Matyjaszewski, Jerome Gromada, Mei Li; Issued July 6, 2004, Filed October 15, 2002
- 6,790,919 Catalyst system for controlled polymerization, Krzysztof Matyjaszewski; Sung Chul Hong; Issued September 14, 2004, Filed October 5, 2001.
- 6,887,962 Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties; Krzysztof Matyjaszewski, Simion Coca, Scott G. Gaynor, Dorota Greszta; Timothy E. Patten, Jin-Shan Wang, Jianhui Xia; Issued May 3, 2005, Filed November 7, 2002.
- 7,019,082 Polymers, supersoft elastomers and methods for preparing the same, Krzysztof Matyjaszewski; Tadeusz Pakula; Issued March 28, 2006, Filed March 28, 2006.
- 7,049,373 Process for preparation of graft polymers, Krzysztof Matyjaszewski, Jean-Francois Lutz, Hosei Shinoda; Issued May 23, 2006, Filed December 21, 2001
- 7,056,455 Process for the preparation of nanostructured materials, Krzysztof Matyjaszewski, Tomasz Kowalewski; David N. Lambeth, James Spanswick, Nicolay V. Tsarevsky; Issued June 6, 2006, Filed April 6, 2002.
- 7,064,166 Process for monomer sequence control in polymerizations, Krzysztof Matyjaszewski, Betul Kirci, Jean Francois Lutz, Tomislav Pintauer; Issued June 20, 2006, Filed October 11, 2002.
- 7,125,938 Atom or group transfer radical polymerization, Krzysztof Matyjaszewski, Scott G. Gaynor, Simion Coca; Issued: October 24, 2006 Filed February 18, 2004
- 7,157,530 Catalyst system for controlled polymerization, Krzysztof Matyjaszewski; Sung Chul Hong; Issued, January 2, 2007, Filed June 3, 2004.
- 7,332,550 Stabilization of transition metal complexes for catalysis in diverse environments, Krzysztof Matyjaszewski, Nicolay Tsarevsky; Issued February 19, 2008, October 10, 2003.
- 7,407,995 Synthesis of MDH-polymer hybrid particles, Jeong-Bin Ok, Krzysztof Matyjaszewski; Issued August 5, 2008, Filed November 3, 2006.
- 7,572,874 Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties; Krzysztof Matyjaszewski, Simion Coca, Scott G. Gaynor, Dorota Greszta; Timothy E. Patten, Jin-Shan Wang, Jianhui Xia; Issued August 11, 2009, Filed February 16, 2005.
- 7,678,869 Atom or group transfer radical polymerization, Krzysztof Matyjaszewski, Scott G. Gaynor, Simion Coca; Issued: March 16, 2010, May 8, 2006.
- 7,795,355 Preparation of functional polymers, Matyjaszewski; Krzysztof, Brent S. Sumerlin; Nicolay V. Tsarevsky;, James Spanswick; Issued September 14, 2010, Filed September 22, 2005.
- 7,825,199 Catalytic processes for the controlled polymerization of free radically (co)polymerizable monomers and functional polymeric systems prepared thereby, Krzysztof Matyjaszewski, Scott G. Gaynor, Hyun-jong Paik, Tomislav Pintauer, Jeff Pyun, Jian Qiu, Mircea Teodorescu, Jianhui Xia, Xuan Zhang, Peter J.Miller; Issued November 2, 2010, Filed March 23, 2000.
- 7,893,173 Polymerization process with catalyst reactivation, Krzysztof Matyjaszewski, Wojciech Jakubowski; James Spanswick; Issued February 22, 2011, Filed March 01, 2007.
- 7,893,174 Atom transfer radical polymerization process. Krzysztof Matyjaszewski, Lindsay Bombalski, Wojciech Jakubowski, Ke Min, James Spanswick, Nicolay V. Tsarevsky; Issued February 22, 2011, Filed September 22, 2005.
- 8,252,880 Atom transfer dispersion polymerization, Krzysztof Matyjaszewski, Ke Min, James Spanswick; Issued August 28, 2012,Filed December 04, 2008.
- 8,273,823 Atom transfer radical polymerization in microemulsion and true emulsion polymerization processes, Krzysztof Matyjaszewski, Ke Min, Issued September 25, 2012, March 01, 2007.
- 8,349,410 Modification of surfaces with polymers, Jinyu Huang, Alan J. Russell, Nicolay V. Tsarevsky, Krzysztof Matyjaszewski; Issued January 8, 2013, Filed August 17, 2007.
- 8,367,051 Preparation of functional gel particles with a dual crosslink network, Krzysztof Matyjaszewski, Ke Min; Jung Kwon Oh, James Spanswick, Nicolay V. Tsarevsky; Issued February 5, 2013, Filed May 15, 2008.
- 8,404,788 Atom transfer radical polymerization process, Krzysztof Matyjaszewski; Lindsay Bombalski; Wojciech Jakubowski; Ke Min; Nicolay V. Tsarevsky; James Spanswick; Issued March 26, 2013, Filed February 14, 2011.
- 8,445,610 Controlled radical polymerization processes, Yungwan Kwak, Renaud Nicolay, Krzysztof Matyjaszewski, Issued May 21, 2013, Filed March 6, 2009.
- 8,816,001 Genetically encoded initiator for polymer growth from proteins, Ryan A. Mehl, Krzysztof Matyjaszewski; Saadyah Averick; August 26, 2014, Application Number 13/788,710 Filed March 7, 2013.
- 8,865,797 Hybrid particle composite structures with reduced scattering, Krzysztof Matyjaszewski, Lindsay Bombalski, Michael R. Bockstaller; Issued October 21, 2014, Application Number 12/451,575 , Filed March 23, 2008.
- 8,871,831 Modification of surfaces with polymers Jinyu Huang, Alan J. Russell, Nicolay V. Tsarevsky, Krzysztof Matyjaszewski; Issued October 28, 2014 Application Number 14/065,370; Filed October 28, 2013.
- 8,962,764 Preparation of functional star macromolecules Krzysztof Matyjaszewski, Haifeng Gao, James Spanswick ; Issued February 24, 2015 Application Number 13/260,504; Filed March 29, 2010
- 8,969,498 Compositions and method of inhibiting polymerization of vinyl-aryl monomers, Nathan T. Kendall, Kishore K. Kar, Mark H. McAdon, Krzysztof Matyjaszewski, Laura Mueller, Charles D Dukes, Issued March 3, 2015 Application Number 13/811,274; Filed July 27, 2011
- 9,243,274 Genetically encoded initiator for polymer growth from proteins; Saadyah Averick, Krzysztof Matyjaszewski and Ryan A. Mehl. Issued January 26, 2016 Application number 14/452,060; Filed August 5, 2014.
- 9,410,020 Processable self-organizing nanoparticle; Krzysztof Matyjaszewski and Michael Bockstaller. Issued August 9, 2016. Application Number 14/373,553; Filed January 28, 2013.
- 9,447,201 Polymerization inhibitor composition and method of inhibiting polymerization of distillable monomers; Kishore K. Kar, Michael D. Cloeter, Stanley O. Fruchey, Richard S. Harner, Krzysztof Matyjaszewski, Renaud Nicolaÿ, and Jaroslav Mosnáček Issued September 20, 2016 Application number 13/147,733. Filed February 18, 2010.
- 9,533,297 Designing Highly Active Ligands for Atom Transfer Radical Polymerization; Krzysztof Matyjaszewski, Yungwan Kwak, Joanna Burdynska, Andrea Elsen and Kristin Schröder. Issued January 3, 2017 Application number 14/379418. Filed February 22, 2013.
- 9,644,042 “Electrochemically Mediated Atom Transfer Radical Polymerization”, Krzysztof Matyjaszewski, Nicola Bortolamei, Andrew Magenau, Armando Gennaro, Abdirisak Ahmed Isse, Issued May 16, 2017, Application number 13/993, 521. Filed December 16, 2011
- 9,765,169 Functionalized polymer hybrids; Das, Subha Ranjan, Saadyah Averick, Dey, Sourav K., Krzysztof Matyjaszewski and Michael Bockstaller. Issued September 19, 2017. Application Number 14/785, 334; Filed April 17, 2014.
- 9,790,305 Site specifically incorporated initiator for growth of polymers from proteins; Saadyah Averick, Krzysztof Matyjaszewski and Ryan A. Mehl. Issued October 17, 2017 Application number 13/788710; Filed March 15, 2013.
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9,969,823 Synthesis and polymerization of vinyl triazolium ionic liquids; David Luebke, Hunaid Nulwala, Krzysztof Matyjaszewski, Brian Adzima. Issued May 15, 2018 Application number 14/951210; Filed November 24, 2015.
- 9,982,070 Aqueous ATRP in the presence of an activator regenerator; Krzysztof Matyjaszewski, Pawel Chmielarz, Dominik Konkolewicz, Pawel Krys, Xiangcheng Pan, Valerie Williams; Issued May 29, 2018 Application number 14/993632; Filed January 14, 2016.
- 10,072,042 Atom transfer radical polymerization under biologically compatible conditions; Krzysztof Matyjaszewski; Saadyah Averick; Antonina Simakova, Issued September 11, 2018 Application number 15/378,537; Filed December 14, 2016.
There are thirteen active applications.
Two of the granted patents were the earliest filed relating to ATRP and dominate the field covering both ATRP process and many products made by CRP.
In the related field of Nitroxide Mediated Polymerization
- 5,910,549 Method for preparation of alkoxyamines from nitroxyl radicals
An expansion of the utility of US Patent 5,910,549 was covered in US 6,512,060 where the use of copper zero to drive the reaction to completion was disclosed (Claim 26) and in US 6,541,580 which discloses replacing the radically transferable atom or group in a copolymer with a thermally labile group, to form a bifunctional macroinitiator (claims 17-18). - 6,288,186 Rate enhancement of nitroxyl radical-mediated polymerization
Published Patent Applications
- WO 2010/111708; Preparation of functional star macromolecules
- WO 2009/111725; Improved controlled radical polymerization process
- WO 2009/111725; Imporved controlled radical polymerization processes
- WO 2009/023353; Hybrid particle composite structures with reduced composite structures with reduced scattering
- WO 2008/148000; Atom transfer dispersion polymerization
- WO 2008/057163; Preparation of functional gel particles with a dual crosslonk network
- WO 2008/021500; Modification of surfaces with polymers
- WO 2007/075817; PCT/US2006/048656 Preparation of block copolymers
- WO 2007/059350; PCT/US2006/044931 Preparation of Alkoxyamines
- WO/2007/052964; PCT/KR2006/004535 20070197693 Synthesis of MDH-polymer hybrid particles
- WO/2007/025310; PCT/US2006/033792 Polymerization process with catalyst reactivation
- WO/2007/025086; PCT/US2006/033152 ATRP in microemulsion and true emulsion polymerization
- WO2004087777; PCT/US2004/009905 20070155926 Degradable polymers
- WO2006086599; 20070106012 Modified Carbon Particles
- WO2005084159; 20060008490 Antimicrobial surfaces and methods for preparing antimicrobial surfaces
- WO2005087819; Atom transfer radical polymerization process
- WO/2005/087818; PCT/US2005/007264 Preparation of functional polymers
- WO/2004/096872; PCT/US2003/032172 Stabilization of transition metal complexes for catalysis in diverse environments
- WO 00/56795; Catalytic processes for the controlled polymerization of free radically (co)polymerizable monomers and functional polymeric systems prepared thereby
Unpublished Patent Applications
There are currently six unpublished patent applications focused on a) stable particles; b) self cleaning biocidal surfaces; c) FRP stars; d) responsive coatings; e) degradable hydrogels and f) graphene structures.