Erin SchumanHHMI Investigator Website
Synapses, the points of contact and communication between neurons, can vary in their size, strength, and number. We are interested in how synapses are modified at the cellular and molecular level. We are also interested in how neuronal circuits change when synapses change their properties.
Chris BurgeWebsite at MIT
The Burge lab integrates computational modeling and experimental methods to investigate the “rules” of RNA splicing that are used by the cellular splicing machinery to identify the precise locations of exons and splice sites. Their research includes studying the mechanisms of splicing regulation, developing improved algorithms to identify genes in genomic sequences, and investigating the regulation of protein expression by the recently discovered class of small non-coding RNAs known as microRNAs.