Sidney StricklandWebsite at The Rockefeller University
Neurodegenerative diseases represent a profound medical problem throughout the world. For example, Alzheimer's disease, Parkinson's disease, and stroke affect millions of people and have severe physical, psychological, and financial consequences for patients and their families. The basic approach of our laboratory is to use mouse models of neurological disease to elucidate the molecular mechanisms by which neuronal function is disrupted in these and other diseases.
Barbara TraskWebsite at the Fred Hutchinson Cancer Research Center
The Trask group studies large-scale facets of genome organization. Our work relies on fluorescence in situ hybridization (FISH), a means of fluorescently tagging specific DNA sequences in chromosomes or nuclei, flow cytometry, a technology for isolating specific chromosomes based on their DNA content, and various tools for genome sequence analysis.