Carnegie Mellon University

biv

An 80-element, high  order computational biventricular heart failure model (left) with dynamic boundary conditions to simulate the tVAD, (top right) before applying rotation and (bottom right) after a net rotation of 45 degrees was applied  in a counterclockwise direction at the time of peak systole (187.5 ms)

strain

Undeformed mesh with maximum principal strains rendered; large coverage case at peak pressure for 75 degree applied rotation; (left) posterior view of longitudinal-transmural cross-sections dividing the anterior and posterior walls in the left ventricle (LAP) and right ventricle (RAP); (right) lateral view of longitudinal-transmural cross-sections (anterior-ANT; posterior-POST) orthogonal to LAP and RAP.

strains2

Finite strains that contribute to large principal strains (maximum component) estimated near base in the LV in deformed state at peak pressure (surfaces are smooth; ribbing indicates deformation from no load state and is an intentional artifact of rendering at low resolution); (left) transmural normal strain (E33) for applied rotation of 75 degrees, indicating stretching normal to the epicardium (red zone); (right) corresponding in-plane shear strain (E12: fiber/cross-fiber); both components and smaller values of other components result in large principal strains.