supported membrane

Biological Physics

Supramolecular Structures Lab
Lösche/Heinrich Group

www.cmu.edu
 
     

Matteo Broccio

 

 

Contact

Carnegie Mellon University
Department of Physics
5000 Forbes Ave
Wean Hall room 6315
Pittsburgh, PA 15213
voice: 412-268-2729
fax: 412-681-0648
email: mbroccio@andrew.cmu.edu

 

Education

Ph.D., Department of Physics, University of Messina, Italy (2005)

Laurea (M.Sc.), Physics, University of Messina, Italy (2000)

 

Research Experience

Oct 2007 - now
Research Associate, Carnegie Mellon University, Department of Physics

Structural and functional characterization of tethered lipid bilayers with neutron reflectometry, electrochemical methods, and surface plasmon resonance. Interaction of β-amyloid oligomers with membranes. Protein reconstitution studies in tethered lipid bilayers.

 
June 2006 - Oct 2007
Research Fellow, University of Messina, Department of Physics
Study of transport parameters in supercooled confined water, protein hydration water and water-alcohol mixtures with Nuclear Magnetic Resonance.

 
Dec 2004 - Feb 2006
Visiting Scientist, MIT, Department of Nuclear Science and Engineering
Neutron scattering study of structure and effective interaction of copolymer micelles. Assessment with Monte Carlo simulations of simple analytical models for the effective interactions of globular proteins in solution.
 

 

Teaching Experience

2008-2009
Course Assistant, Carnegie Mellon University, Department of Physics
Introduction to Biological Physics (Course IDs: 33-441/03-439)
 

 

Recent publications

  • P. Cizas, R. Budvytyte, R. Morkuniene, R.G. Moldovan, M. Broccio, M. Lösche, G. Niaura, G. Valincius, and V. Borutaite, “Size-dependent neurotoxicity of β-amyloid oligomers“, Archives of Biochemistry and Biophysics, 496, 84-92 (2010)
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  • C. Corsaro, J. Spooren, C. Branca, N. Leone, M. Broccio, C. Kim, S.H. Chen, H.E. Stanley and F. Mallamace, “Clustering dynamics in water/methanol mixtures: a nuclear magnetic resonance study at 205 K < T < 295 K”, J. Phys. Chem. B , 112 (34), 10449-10454 (2008).
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  • F. Mallamace, C. Corsaro, M. Broccio, C. Branca, N. Gonzalez-Segredo, J. Spooren, S.H. Chen, and H.E. Stanley, “NMR evidence of a sharp change in a measure of local order in deeply supercooled confined water ”, Proc. Natl. Acad. Sci. USA, 105 (35), 12725-12729 (2008).
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  • F. Mallamace, C. Branca, M. Broccio, C. Corsaro, C.-Y. Mou, S.-H. Chen, “ The anomalous behavior of the density of water in the range 30 K < T < 373 K”, Proc. Natl. Acad. Sci. USA, 104 (47), 18387-18391 (2007).
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  • F. Mallamace, S.-H. Chen, M. Broccio, C. Corsaro, V. Crupi, D.Majolino, V. Venuti, P. Baglioni, E. Fratini, C. Vannucci, H.E. Stanley, “Role of the solvent in the dynamical transitions of proteins: The case of the lysozyme-water system”, Journal of Chemical Physics, 127, 045104 (2007).
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  • S.-H. Chen, M. Broccio, Y. Liu, P. Baglioni, E. Fratini, “The two-Yukawa model and its applications: the cases of charged proteins and copolymer micellar solutions”, Journal of Applied Crystallography, 40, S321-326 (2007).
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  • F. Mallamace, M. Broccio, C. Corsaro, V. Crupi, D. Majolino, V. Venuti, S.-H. Chen, “Evidence of the low-density liquid phase in supercooled water”, Proc. Natl. Acad. Sci. USA, 104, 424-428 (2007).
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  • F. Mallamace, M. Broccio, C. Corsaro, A. Faraone, L. Liu, C.-Y. Mou, S.-H. Chen, “Dynamical properties of confined supercooled water: an NMR study”, J. Phys.: Condens. Matt. 18, S2285 (2006).
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  • S.-H. Chen, F. Mallamace, C.-Y Mou., M. Broccio, C. Corsaro, A. Faraone, L. Liu, “The Violation of Stokes-Einstein Relation in Supercooled water”, Proc. Natl. Acad. Sci. USA, 103, 12974-12978 (2006).
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  • F. Mallamace, M. Broccio, C. Corsaro, A. Faraone, U. Wanderlingh, L. Liu, C.-Y. Mou, S.-H. Chen, “The fragile-to-strong dynamic crossover transition in confined water: nuclear magnetic resonance results”, J. Chem. Phys. 124, 161102 [1-4] (2006).
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  • M. Broccio, D. Costa, Y. Liu, S.-H. Chen, “The structural properties of two-Yukawa fluid: Simulation and analytical results”, J. Chem. Phys. 124, 084501[1-9] (2006).

 

Awards and Affiliations

  • Member of American Physical Society and Biophysical Society.
  • 2006 Cozzarelli Prize co-recipient, Applied Physics section, awarded by editorial board of Proceedings of the National Academy of Sciences USA.