supported membrane

Biological Physics

Supramolecular Structures Lab
Lösche Group

www.cmu.edu
 
     

Lab publications

 

2007+

G. Valincius, F. Heinrich, R. Budvytyte, D. J. Vanderah, D. J. McGillivray, Y. Sokolov, J. E. Hall, and M. Lösche, Soluble amyloid b oligomers affect dielectric membrane properties by bilayer insertion and domain formation: Implications for cell toxicity, Biophys. J., in press. download BioFast preprint / download supplement

I. K. Vockenroth, C. Ohm, J. W. F. Robertson, D. J. McGillivray, M. Lösche, and I. Köper, Stable insulating tethered bilayer lipid membranes, Biointerphases 3 (2008), FA68 – FA73. download paper

D. J. McGillivray, G. Valincius, D. J. Vanderah, W. Febo-Ayala, J. T. Woodward, F. Heinrich, J. J. Kasianowicz, and M. Lösche, Molecular-scale structural and functional characterization of sparsely tethered bilayer membranes, Biointerphases 2 (2007), 21 – 33. download paper / download supplement

2004 – 2006

J. A. Dura, D. J. Pierce, C. F. Majkrzak, N. Maliszewskyj, D. J. McGillivray, M. Lösche, K. V. O’Donovan, M. Michailescu, U. A. Perez-Salas, D. L. Worcester, and S. H. White, AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences, Rev. Sci. Instrum. 77 (2006), 074301.

J. Pittler, W. Bu, D. Vaknin, A. Travesset, D. J. McGillivray, and M. Lösche, Charge inversion at minute electrolyte concentrations, Phys. Rev. Lett. 97 (2006), 046102.

G. Valincius, D. J. McGillivray, W. Febo-Ayala, D. J. Vanderah, J. J. Kasianowicz, and M. Lösche, Enzyme activity to augment the characterization of tethered bilayer membranes, J. Phys. Chem. B  110 (2006), 10213 – 10216.

M. Dyck and M. Lösche, Interaction of the neurotransmitter, neuropeptide Y, with phospholipid membranes: Film balance and fluorescence microscopy studies, J. Phys. Chem. B  110 (2006), 22143 – 22151.

M. Dyck, A. Kerth, A. Blume, and M. Lösche, Interaction of the neurotransmitter, neuropeptide Y, with phospholipid membranes: Infrared spectroscopic characterization at the air/water inter­face, J. Phys. Chem. B  110, 22152 – 22159.

T. Gutberlet and M. Lösche, Complex biomimetic structures at fluid surfaces and sold/liquid interfaces, chapt. 14 in: Neutron Scattering in Biology, J. Fitter, T. Gutberlet, J. Katsaras, Eds. (Springer, New York, 2006), 283 – 306.

M. Dyck, P. Krüger and M. Lösche, Headgroup organization and hydration of methylated phosphatidylethanolamines in Langmuir monolayers, Phys. Chem. Chem. Phys. 7 (2005), 150 – 156.

P. Krüger and M. Lösche, Characterization of Floating Surface Layers of Lipids and Lipopolymers by Surface-Sensitive Scattering, in: Lecture Notes in Physics, Vol. 634, Eds.: R. Haberlandt, D. Michel, A. Pöppl and R. Stannarius, Springer, New York (2004), 395 – 438.

T. M. Fischer and M. Lösche, Pattern Formation in Langmuir Monolayers Due to Long-Range Electrostatic Interactions, in: Lecture Notes in Physics, Vol. 634, Eds.: R. Haberlandt, D. Michel, A. Pöppl and R. Stannarius, Springer, New York (2004), 383 – 394.

2001 – 2003

D. Vaknin, P. Krüger and M. Lösche, Anomalous x-ray reflectivity characterization of ion distribution at biomimetic membranes, Phys. Rev. Lett. 90 (2003), 178102.

M. Ferreira, P. Dynarowicz-Latka, J. Miñones Jr., W. Caetano, K. Kita, M. Schalke, M. Lösche, and O. N. Oliveira Jr., On the origin of the plateau in surface-pressure isotherms of aromatic carboxylic acids, J. Phys. Chem. B 106 (2002), 10395 – 10400.

M. Lösche, Surface-sensitive X-ray and neutron scattering characterization of planar lipid model membranes and lipid/peptide interactions. In: Current Topics in Membranes, Vol. 52, Ch. 5, Eds.: S. A. Simon and T. J. McIntosh, Academic Press, San Diego (2002), 115 – 160.

P. Esquinazi, A. Setzer, R. Höhne, C. Semmelhack, Y. Kopelevich, D. Spemann, T. Butz, B. Kohlstrunk, and M. Lösche, Weak ferromagnetism in oriented graphite samples, Phys. Rev. B 66 (2002), 024429.

P. Krüger, J. E. Baatz, R. A. Dluhy, and M. Lösche, Effect of hydrophobic surfactant peptides SP–B and SP–C on binary phospholipid monolayers. II. Molecular machinery at the air/water interface, Biophys. Chem. 99 (2002), 209 – 228.

M. Weygand, K. Kjaer, P. B. Howes, B. Wetzer, D. Pum, U. B. Sleytr, and M. Lösche, Structural reorganization of phospholipid headgroups upon recrystallization of an S-layer lattice, J. Phys. Chem. B 106 (2002), 5793 – 5799.

R. Stannarius, R. Köhler, U. Dietrich, M. Lösche, C. Tolksdorf, and R. Zentel, Structure and elastic properties of smectic liquid crystalline elastomer samples, Phys. Rev. E, 65 (2002), 041707.

Z. Khattari, P. Heinig, S. Wurlitzer, P. Steffen, M. Lösche, and T. M. Fischer, Wetting in asymmetric quasi-2D systems, Langmuir 18 (2002), 2273 – 2279.

M. Lösche and P. Krüger, Morphology of Langmuir monolayer phases, in: Lecture Notes in Physics, Vol. 600, Eds.: K. R. Mecke and D. Stoyan, Springer, New York (2002), 159 – 178.

R.-J. Zhang, P. Krüger, B. Kohlstrunk, and M. Lösche, Self-organized lateral patterning of a rare earth complex and stearic acid in Langmuir films, ChemPhysChem 2 (2001), 452 – 457.

W. Caetano, M. Ferreira, M. Tabak, M.I. Mosquera Sanchez, O.N. Oliveira Jr., P. Krüger, M. Schalke, and M. Lösche, Cooperativity of phospholipid reorganization upon interaction of dipyridamole with surface monolayers on water, Biophys. Chem. 91 (2001), 21 – 35.

W. Lehmann, H. Skupin, E. Gebhard, C. Tolksdorf, R. Zentel, P. Krüger, M. Lösche, and F. Kremer, Giant lateral electrostriction in ferroelectric liquid crystalline elastomers, Nature 410 (2001), 447 – 450.

E. Politsch, G. Cevc, A. Wurlitzer, and M. Lösche, Conformation of polymer brushes at aqueous surfaces determined with x-ray and neutron reflectometry. I. Novel data evaluation procedure for polymers at interfaces, Macromolecules 34 (2001), 1328 – 1333.

A. Wurlitzer, E. Politsch, S. Hübner, P. Krüger, M. Weygand, K. Kjaer, P. Hommes, O. Nuyken, G. Cevc, and M. Lösche, Conformation of polymer brushes at aqueous surfaces determined with x-ray and neutron reflectometry. II. High density phase transition of lipopolyoxazolines, Macromolecules 34 (2001), 1334 – 1342.

P. Krüger, M. Schalke, J. Linderholm, and M. Lösche, Multipurpose x-ray reflectometer optimized for the characterization of organic surface films on aqueous subphases, Rev. Sci. Instrum. 72 (2001), 184 – 192.

1997 – 2000

M. Lösche and M. Schalke, Structural models of lipid surface monolayers from x-ray and neutron reflectivity measurements, Adv. Colloid Interf. Sci. 88 (2000), 243 – 274.

P. Krüger and M. Lösche, Molecular chirality and the domain shapes in lipid monolayers on aqueous surfaces, Phys. Rev. E 62 (2000), 7031 – 7043.

G. Marshall, E. Teer, C.M. Knobler, M. Schalke, and M. Lösche, Phase diagrams for monolayers of long-chain thioacetates, Colloids Surf. A 171 (2000), 41– 48.

T. Gutberlet, A. Wurlitzer, U. Dietrich, E. Politsch, G. Cevc, R. Steitz, and M. Lösche, Organisation of tethered polyoxazoline polymer brushes at the air/water interface, Physica B 283 (2000), 37 – 39.

A. Wurlitzer, E. Politsch, G. Cevc, T. Gutberlet, K. Kjaer, and M. Lösche, Neutron and x-ray reflection from surface monolayers of a lipopolyoxazoline, Physica B 276–278 (2000), 343 – 344.

M. Schalke, P. Krüger, M. Weygand, and M. Lösche, Submolecular organization of DMPA in surface monolayers: Beyond the two-layer model. Biochim. Biophys. Acta 1464 (2000) 113 – 126.

M. Weygand, M. Schalke, P.B. Howes, K. Kjaer, J. Friedmann, B. Wetzer, D. Pum, U.B. Sleytr, and M. Lösche, Coupling of protein sheet crystals (S-layers) to phospholipid monolayers. J. Mater. Chem. 10 (2000) 141 – 148.

V. Hartmann, M. Lösche, S.V. Mello, and O.N. Oliveira, Jr., UV/Vis and SFM studies on  Langmuir monolayers and Langmuir-Blodgett films of 16-mer aniline and o-pentadecylaniline blends. Mater. Sci. Engin. C. 8/9 (1999), 425 – 429.

P. Krüger, M. Schalke, Z. Wang, R.H. Notter, R.A. Dluhy, and M. Lösche, Effect of hydrophobic surfactant proteins SP–B and SP–C on binary phospholipid monolayers. I. Fluorescence and darkfield microscopy. Biophys. J. 77 (1999), 903 – 914.

S.A.W. Verclas, P.B. Howes, K. Kjaer, A. Wurlitzer, M. Weygand, G. Büldt, N.A. Dencher, and M. Lösche, Grazing incidence X-ray diffraction from a single layer of purple membrane at the air/water interface. J. Mol. Biol. 287 (1999), 837 – 843.

M. Weygand, B. Wetzer, D. Pum, U.B. Sleytr, K. Kjaer, P.B. Howes, and M. Lösche, Bacterial Surfacelayer protein coupling to lipid membranes: X-ray reflectivity and grazing incidence diffraction studies. Biophys. J. 76 (1999), 458 – 468.

M. Lösche, J. Schmitt, G. Decher, W.G. Bouwman, and K. Kjaer. Detailed structure of molecularly thin polyelectrolyte multilayer films on solid substrates as revealed from neutron reflectometry. Macromolecules 31 (1998), 8893 – 8906.

B. Wetzer, A. Pfandler, E. Györvary, D. Pum, M. Lösche, and U.B. Sleytr, S-layer reconstitution at phospholipid monolayers. Langmuir 14 (1998), 6899 – 6906.

C. Lautz, T.M. Fischer, M. Weygand, M. Lösche, P. Howes, and K. Kjaer, Determination of alkyl chain tilt angles in Langmuir monolayers: A comparison of Brewster angle autocorrelation spectroscopy and x-ray diffraction. J. Chem. Phys. 108 (1998), 4640 – 4646.

A. Diederich and M. Lösche, Novel biosensoric devices based on molecular protein hetero-multilayer films. Adv. Biophys. 34 (1997), 205 – 230.

M. Lösche, Protein monolayers at interfaces, Curr. Opinion Solid State Mater. Sci. 2 (1997), 546 – 556.

A. Diederich, C. Sponer, D. Pum, U.B. Sleytr, and M. Lösche, Reciprocal influence between the protein and lipid components of a lipid-protein membrane model. Colloids and Surfaces B: Biointerfaces 6 (1996), 335 – 346.

 

 

Journal group reviews
(internal downloads only)

Guo et al., Molecular diffusion measure-ment in lipid bilayers over wide concen-tration ranges: ..., ChemPhysChem 9 (2008), 721. download
(Radu Moldovan, May 14, 2008)

Wiegand et al., Electrical properties of supported lipid bilayer membranes, J. Phys. Chem. B 106 (2002), 4245. download
(Haw Zan Goh, April 23, 2008)

Beerlink et al., X-ray structure analysis of free-standing lipid membranes ..., Langmuir 24 (2008), 4952. download
(Markus Weygand, April 9, 2008)