Carnegie Mellon University

Integrated Innovation Institute

Engineering + Design + Business

Integrated Innovation Institute

Jason Smith

Jason Smith

Instructor of Integrated Innovation, Associate Director of Partnerships

Address
4612 Forbes Avenue,
Pittsburgh, PA

Bio

At the Integrated Innovation Institute, Jason teaches and mentors the next generation of integrated innovators in our MIIPS program. Jason is also III's Associate Director of Partnerships, responsible for recruiting world-class projects and partnerships for the Institute.

Prior to joining the Institute in 2017, Jason was a research faculty member in the Engineering Research Accelerator at CMU where he researched regenerative medicine, wound healing, and biosensors. Prior to joining CMU, he spent ten years at two Pittsburgh-based medical device and biologics start-up companies, Cohera Medical and Carmell Therapeutics. At Carmell, he directed the company’s research and development, preclinical testing, pilot manufacturing, quality control, and intellectual property efforts. He was awarded multiple Phase 1 and Phase 2 SBIR grants, which funded the development of the company’s first product, leading to its successful first-in-man clinical trial. 

Jason was born and raised in central Illinois. In his free time, he enjoys working with stained glass, cooking, music, biking, and traveling.

Advice for Future Innovators

"Observe. The next great idea is often a simple one that's just waiting for us to see it."

Areas of Expertise

Regenerative Medicine, Biomaterials, Medical Devices, Innovation

Integrated Innovation Courses

  • Integrated Product Development (IPD) Methods
  • Integrated Product Development (IPD) Capstone
  • Master's Essay
  • Medical Device Innovation

Education

  • Postdoctoral Fellowship in Regenerative Medicine - Carnegie Mellon University
  • Doctor of Philosophy (PhD) in Chemical Engineering - University of Delaware
  • Bachelor of Science in Chemical Engineering - University of Illinois at Urbana-Champaign

Certifications

  • Certified Project Management Professional (PMP) - Project Management Institute

Research

Jason is researching how to repurpose current FDA-approved materials to make bandages that better promote healing, reduce bacterial contamination, and better communicate the state of the wound to both the patient and healthcare provider.

Publications

  • Schwartzman D, Badhwar V, Kormos R. Smith J, Campbell P, Weiss L. 2015. A Plasma-based amiodarone-impregnated material decreases susceptibility to atrial fibrillation in a post-cardiac surgery model. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 11(1): 59-63.
  • Schwartzman D, Pasculle AW, Ceceris KD, Smith JD, Weiss LE, Campbell PG. 2015. An off-the-shelf plasma-based material to prevent pacemaker pocket infection. Biomaterials 60:1-8.
  • Smith JD, Weiss LE, Burgess JE, West AI, and Campbell PG. 2012. Biologically active blood plasma-based biomaterials as a new paradigm for tissue repair therapies. Disruptive Science and Technology. 1(3): 1-11.
  • Smith JD, Chen A, Ernst LA, Waggoner AS, and Campbell PG. 2007. Immobilization of Aprotinin to Fibrinogen as a Novel Method for Controlling Degradation of Fibrin Gels. Bioconj. Chem. 18(3): 695-701.
  • Smith JD, and Robinson AS (2002). Overexpression of an Archaeal Protein in Yeast: Secretion Bottleneck at the ER. Biotech. Bioeng. 79 (7): 713-723.
  • Smith JD, Fisher GW, Waggoner AS, and Campbell PG. 2007. The use of quantum dots for analysis of chick CAM vasculature. Microvascular Research 73: 75-83.
  • Smith JD, Melhem ME, Magge KT, Waggoner AS, and Campbell PG. 2007. Improved growth factor directed vascularization into fibrin constructs through inclusion of additional extracellular molecules. Microvascular Research 73: 84-94.
  • Jadlowiec J, Dongell D, Smith J, Conover C, and Campbell P. 2005. Pregnancy-associated plasma protein-A is involved in matrix mineralization of human adult mesenchymal stem cells and angiogenesis in the chick chorioallantoic membrane Endocrinology. 146(9):3765-72.
  • Smith JD, Richardson NE, and Robinson AS. 2005 Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress. Biochim Biophys Acta. 2005 Aug 31;1752(1):18-25
  • Smith JD, Tang BC, and Robinson AS. 2004. Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast. Biotechnol Bioeng. 85(3):340-50.

Patents

  • Hydrophilic Biodegradable Adhesives. Inventors: Beckman EJ and Smith JD. Patent # 8,652,293. Issue Date: February 18, 2014. Application # 13/440,470. Filed April 2012.
  • Methods and Apparatus for Manufacturing Plasma-Based Plastics and Bioplastics Therefrom. Inventors: Campbell PG, Burgess JE, Weiss LE, Smith JD.
    • Patent # 9,364,503. Issue date: June 14, 2016. US Application # 14/570,586. Filed December 15, 2014
    • Patent # 8,911,789. Issue date: Sept. 10, 2013. US Application # 13/792,691. Filed March 11, 2013.
    • Patent # 8,529,961. Issue date: Sept. 10, 2013. US Application # 13/177,147. Filed July 6, 2011.
    • Patent # 8,529,958. Issue date: Sept. 10, 2013. US Application # 13/177,029. Filed July 6, 2011.
    • Patent # 8,529,959. Issue date: Sept. 10, 2013. US Application # 13/177,061. Filed July 6, 2011.
    • Patent # 8,529,960. Issue date: Sept. 10, 2013. US Application # 13/177,090. Filed July 6, 2011.
    • Patent # 8,529,956. Issue date: Sept. 10, 2013. US Application # 12/104,728. Filed April 17, 2008.
    • Patent # 8,293,530. Issue date: Oct 23, 2012. US Application # 11/873,751. Filed October 17, 2007.