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Adam W. Feinberg

Adam W. Feinberg

Professor of Materials Science & Engineering and Biomedical Engineering

  • Scott Hall - 4N109
  • 412-268-4897
Address
Carnegie Mellon University
Pittsburgh, PA 15213-3890

Bio

Research Areas:  Manufacturing & Materials Microstructure | Soft, Nanostructured & Bioactive Materials

Dr. Feinberg earned a BS in Materials Science and Engineering from Cornell University in 1999, followed by a Masters (2002) and Ph.D. (2004) in Biomedical Engineering from the University of Florida, where his doctoral work was focused on engineering cell-material interactions to prevent and enhance adhesion. He was then a Postdoctoral Fellow at Harvard University from 2005 to 2010, where he developed new biomaterials and cardiac tissue engineering strategies for 3-dimensional myocardial regeneration, with a focus on stem cell-based approaches. Dr. Feinberg joined CMU in the fall of 2010 as an Assistant Professor with joint appointments in Biomedical Engineering and Materials Science and Engineering.

Education

Ph.D. , Biomedical Engineering from the University of Florida, 2004

Research

We develop materials-based, regenerative strategies with the goal of engineering the self-organization and self-assembly of various cell types into tissue structures and understanding the emergence of higher-order function in neuromuscular and cardiovascular systems. Our specific focus is on the interaction of cells and tissues with engineered materials and determining how cells sense, respond and modulate their environment. This is a problem that spans from the molecular (nano) to the tissue (macro) level where we try to elucidate how biochemical, electrical and mechanical signals are propagated across spatiotemporal scales.

Current efforts are focused on the following areas.
  • 3-dimensional nano/micro structured tissue engineering scaffolds using protein-based materials
  • Engineered skeletal muscle soft robotic devices and bioprosthetics
  • Stem cell differentiation and engineered morphogenesis of cardiovascular tissues

Publications

Stretch-dependent changes in molecular conformation in fibronectin nanofibers
Szymanski JM, Sevcik EN, Zhang K and Feinberg AW. Biomaterials Science, 5, 2017, pp 1629-1639.

3D Printing PDMS Elastomer in a Hydrophilic Support Bath via Freeform Reversible Embedding| [PDF]
Hinton TJ, Hudson A, Pusch K, Lee A and Feinberg AW. ACS Biomaterials Science & Engineering, 2 (10), 2016, pp 1781–1786.

Defined Micropatterning of ECM Protein Adhesive Sites on Alginate Microfibers for Engineering Highly Anisotropic Muscle Cell Bundles | Cover Image
Patil P,  Szymanski JM and Feinberg AW. Advanced Materials Technologies, 1(4), 2016, pp 1-5.

Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels | [PDF]
Hinton TJ, Jallerat Q, Palchesko RN, Park JH, Grodzicki MS, Shue HJ, Ramadan MH, Hudson AR and Feinberg AW. Science Advances, 1(9), 2015, e1500758.

Conformal Nanopatterning of Extracellular Matrix Proteins onto Topographically Complex Surfaces | [PDF]
Sun Y, Jallerat Q, Szymanksi JM and Feinberg AW. Nature Methods, 2(12), 2015, pp 134-136.