Pekkan Cardiovascular Biofluids Group, Biomedical Engineering Deparment, Carnegie Mellon University

Virtual Surgical Planning: Tools for 3D anatomy editing and hemodynamic analysis for the mastery of complex cardiovascular surgeries

Anatomical variation and geometrical complexity of the cardiovascular system is a significant challenge for advancing the traditional surgical decision making process and achieve a quantitative pre-surgical patient-specific outcome assessment. We hypothesize that computer aided tools that simulate and quantitatively analyze reconstructive treatment alternatives in an interactive computer medium without in vivo execution can assist the surgical decision making process, reduce trial-and-error at the operating room for complex cardiovascular reconstructions. Pre-interventional noninvasive and virtual techniques place within reach the ability to avoid pitfalls and achieve optimal surgical outcomes. Advanced patient-specific analysis techniques integrated with the three-dimensional image modalities are available only for static anatomies and the geometrical complexity remains to be the biggest challenge in their routine clinical use. Sketch based geometrical tools for morphology editing, surgical training and quantitative analysis are being developed through our unique collaboration with Prof. Levent Burak Kara with the objective to facilitate systematic innovation in surgical design, vascular repair, palliative treatment planning and enable routine multi-scale patient specific computational modeling for functional analysis.

hemodynamic surgical planning

Advanced anatomical editing/sculpturing tools are integrated with the computational hemodynamic performance analysis and mesh generation (with Prof. Jessica Zhang). Improved boundary conditions for real-time comparative computational fluid dynamic simulations and optimization stategies are being studied on our immersed boundary parallel cardiovascular CFD code developed by Prof. Fotis Sotiropoulos.