Hong Cho - Matyjaszewski Polymer Group - Carnegie Mellon University

Hong Cho

Address:
Carnegie Mellon University
4400 Fifth Avenue
Mellon Institute
Pittsburgh, PA 15213
Office: MI-810
Phone: (412) 268-4391

Education

Ph.D. candidate (Chemistry) Carnegie Mellon University, Pittsburgh, PA, USA
Research: Synthesis of Cationic Star Polymers for siRNA Delivery

Advisor: Prof. Krzysztof Matyjaszewski

08.2008 - now

M.S. (Polymer Science and Engineering) Pusan National University, Busan, Korea
Advisor: Prof. Hyun-jong Paik
02.2008

B.S. (Polymer Science and Engineering) Pusan National University, Busan, Korea
02.2005

Publications

  1. H.Y. Cho et al., Multifunctional Biocompatible Star and Graft Copolymers for a Potential siRNA Delivery, in preparation.
  2. H.Y Cho et al., Synthesis of Star-like Polymers with a Linear Backbone: Effect of Macromonomer Concentration and Solvent, in preparation.
  3. F. Snijkers, H.Y. Cho, A. Nese, K. Matyjaszewski, D. Vlassopoulos, Rheological Study of Star Polymers with Different Core Shape, in preparation.
  4. E.W. Hsu, S. Liu, A.R. Shrivats, A.C.S. Watt, S. McBride, S.E. Averick, H.Y. Cho, K. Matyjaszewski, J.O. Hollinger, Cationic Nanostructured Polymers for siRNA Delivery in Murine Calvarial Pre-Osteoblasts, Journal of Biomedical Nanotechnology 2014, 10, 1130-1136.
  5. S. Park, H.Y.Cho, K. Wegner,J. Burdynska, A.J.D. Magenau, H.-j. Paik, S. Jurga, K. Matyjaszewski,Star Synthesis Using Macroinitiators via Electrochemically Mediated Atom Transfer Radical Polymerization, Macromolecules 2013, 46, 5856-5860.
  6. M. Makrocka-Rydzyk, A. Wypych, M. Dobies, M. Jancelewicz, S. Jurga, H.Y. Cho, H. Gao, K. Matyjaszewski, Molecular Dynamics in PBA/PEO Miktoarm Star Copolymers, Polymer 2013, 54, 3341-3349.
  7. H.Y. Cho, S.E. Averick, E. Paredes, K. Wegner, A. Averick, S. Jurga, S.R. Das, L. Matyjaszewski, Star Polymers with a Cationic Core Prepared by ATRP for Cellular Nucleic Acids Delivery, Biomacromolecules 2013, 14, 1262-1267.
  8. M.A. Kadir, S.J. Kim, E.-J. Ha, H.Y. Cho, B.-S. Kim, D. Choi, S.-G. Lee, B.G. Kim, S.-W. Kim, H.-j. Paik, Encapsulation of Nanoparticles Using Nitrilotriacetic Acid End-Functionalized Polystyrenes and Their Application for the Separation of Proteins, Advanced Functional Materials 2012, 22, 4032-4037.
  9. S.E. Averick, E. Paredes, A. Irastorza, A.R. Shrivats, A. Srinivasan, D.J. Siegwart, A.J.D. Magenau, H.Y. Cho, E. Hsu,  A. Averick, J. Kim, S. Liu, J.O. Hollinger, S.R. Das, K. Matyjaszewski, Preparation of Cationic Nanogels for Nucleic Acid Delivery, Biomacromolecules 2012, 13, 3445-3449.
  10. H.Y. Cho, A. Srinivasan, J. Hong, E. Hsu, S. Liu, A. Shrivats, D. Kwak, A.K. Bohaty, H.-j. Paik, J.O. Hollinger, K. Matyjaszewski, Synthesis of Biocompatible PEG-Based Star Polymers with Cationic and Degradable Core for siRNA Delivery, Biomacromolecules 2011, 12, 3478-3486.
  11. M. Makrocka-Rydzyk, A. Wypych, K. Szpotkowski, M. Kozak, S. Jurga, H. Gao, H.Y. Cho, K. Matyjaszewski, Structural Studies of Poly(butyl acrylate)-Poly(ethylene oxide) Miktoarm Star Polymers, Polymer 2011, 52, 5513-5520.
  12. H.Y. Cho, M.A. Kadir, B.-S. Kim, H.S. Han, S. Nagasundarapandian, Y.-R. Kim, S.B. Ko, S.-G. Lee, H.-j. Paik, Synthesis of Well-Defined (Nitrilotriacetic Acid)-End-Functionalized Polystyrenes and Their Bioconjugation with Histidine-Tagged Green Fluorescent Proteins, Macromolecules 2011, 44, 4672-4680.
  13. J. Burdynska, H.Y. Cho, L. Mueller, K. Matyjaszewski, Synthesis of Star Polymers Using ARGET ATRP, Macromolecules 2010, 43, 9227-9229.
  14. S. Park, H.Y. Cho, J. A. Yoon, Y. Kwak, A. Srinivasan, J. O. Hollinger, H.-j. Paik, K. Matyjaszewski, Photo-Cross-Linkable Thermoresponsive Star Polymers Designed for Control of Cell-Surface Interactions, Biomacromolecules 2010, 11, 2647-2652.
  15. H.Y. Cho, H. Gao, A. Srinivasan, J. Hong, S.A. Bencherif, D. J. Siegwart, H.-j. Paik, J. O. Hollinger, K.Matyjaszewski, Rapid Cellular Internalization of Multifunctional Star Polymers Prepared by Atom TransferRadical Polymerization, Biomacromolecules 2010, 11, 2199-2203.
  16. H.Y. Cho, B.H. Han, I. Kim, H.-j. Paik, New Tridentate Ligands with Mixed Donor Atoms for Cu-based Atom Transfer Radical Polymerization, Macromolecular Research 2006, 14, 539-544.

Patents

  1. Method and apparatus for purification of carbon nanotubes. Paik, H.-j.; Choi, Jin Hwan; Kim, Bog Gi; Oh, Saet Byeol; Park, Chun Ho; Kim, Mi Jin; Jung, Tae Ho; Chang, Jun Ho; Cho, Hong Y.; Han, Jung Hun; Cho, Soo Kyung. KR Pat. 0593829
  2. Method for modifying a surface of carbon nanotube. Paik, H.-j.; Kim, Bog Gi; Choi, Jin Hwan; Oh, Saet Byeol; Park, Chun Ho; Kim, Mi Jin; Jung, Tae Ho; Chang, Jun Ho; Cho, Hong Y.; Han, Jung Hun; Cho, Soo Kyung. KR Pat. 0652861
  3. Multifunctional microcarrier for water dispersive nanoparticles and encapsulation method for the same. Paik H.-j.; Lee, Sun-Gu; Kim, Su jeong; Lee, Ji yeon; Ryu, Euidock; Lee, Hyo Kyung; Kim, Hye Lynn; Jo, In-sung; Cho, Hong Y. Pat. 0072274
  4. (Nitrilotriacetic Acid)-end-functionalized polymer, synthesis method thereof and analyzing, separating or purifying method of protein using the same. Paik, H.-j; Yoo, Hyun Oh; Kim, Jung Ahn; Lee, Sun-Gu; Cho, Hong Y.; Lee, Hyo Kyung; Kim, Su jeong; Aleya, Hasneen; Kim, Yu Jin. (filed)

Presentations

  1. Polymers Prepared by ATRP for Nucleic Acid Delivery, CRP Consortium, Apr. 2013, Pittsburgh, PA
  2. Cationic Polymers for Nucleic Acid Delivery, CRP Consortium, Oct. 2012, Pittsburgh, PA
  3. Designing of Polymeric Materials for Nucleic Acid Delivery, CRP Consortium, Apr, 2012, Pittsburgh, PA
  4. Star Polymers for siRNA Delivery, CRP Consortium, Oct. 2011, Pittsburgh, PA
  5. Well-defined (Nitrilotriacetic Acid)-end-functionalized Polystyrenes and Their Bioconjugation with Histidine Tagged Proteins, 242nd ACS National Meeting, 2011, Denver, CO
  6. Bioconjugation of ATRP for Biomedical Application, CRP Consortium, Apr. 2011, Pittsburgh, PA
  7. PEG Star Polymers with Cationic Core for siRNA Delivery System, CRP Consortium, Oct. 2010, Pittsburgh, PA
  8. PEO Containing Cationic Star Polymers for siRNA Delivery, CRP Consortium, Sep. 2009, Pittsburgh, PA
  9. Synthesis and Characterization of (Nitrilotriacetic Acid)-End-Functionalized Polystyrene, IUPAC International Symposium on Advanced Polymer for Emerging Technologies (PKS 30), Oct. 2006, Busan, Korea
  10. Synthesis of Nitrilotriacetic Acid-end-functionalized Polystyrene Using Atom Transfer Radical Polymerization, 232nd ACS National Meeting, 2006, San Francisco, CA
  11. New Catalytic System for Atom Transfer Radical Polymerization, 3rd International Symposium on Advanced Materials in Asia-Pacific Rim, May 2006, Ulsan, Korea
  12. Development of New Catalysts for Atom Transfer Radical Polymerization, Pusan-Kyeongnam / Kyushu-Seibu Joint Symposium on High Polymers (12th) and Fibers (10th), Nov. 2005, Kitakyusu Fukuoka, Japan

Experience

  • Visiting scientist: Coates group, Department of Chemistry and Chemical Biology, Cornell University (Oct 2006 - Feb 2007)
  • Visiting scientist: Cos Biotech (Organic synthesis, Dec 2005)
  • Military service (Dec 1999 – Feb 2002)

Research Skills

  • Synthesis of Multifunctional Polymer with Complex Architectures
  • Polymer Characterization Techniques (GPC with RI or MALLS, GC, HPLC, FT-IR, NMR, DLS, Zeta-Potential, DSC, TGA, TEM and SEM)
  • Polymer Encapsulation of Nanoparticles
  • Biological Skills (Polyplex, Imaging and Cell Handling)
  • Bioconjugation (Peptide-Polymer and Protein-Polymer)

Awards

  • 2006 Best poster award, 2006 IUPAC International Symposium on Advanced Polymer for Emerging Technologies Commemorating the 30th Anniversary of the Polymer Society of Korea
  • 2005 Best poster award, Pusan-Kyeongnam / Kyushu-Seibu Joint Symposium on High Polymers (12th) and Fibers (10th)
  • 2005 University scholarship for graduate school, Pusan National University
  • 2004 University scholarship, Pusan National University
  • 2003 University scholarship, Pusan National University
  • 1998 University scholarship, Pusan National University