We take advantage of the interdisciplinary nature of the study of DNA and other nucleic acids, along with the increased public awareness of DNA, to create interesting and exciting activities and experiments that teach fundamental concepts covered in the mathematics, science and technology curriculum of K-12 educational institutions. One of our goals is to attract and retain 4th-12th grade students to science by exposing them to modern and exciting, state-of-the art aspects of nucleic acids science. We would like to foster their learning of fundamental concepts of mathematics, science and engineering and their appreciation of collaboration and interdisciplinary work in human endeavors. We would like to create continuous opportunities for students to participate in a educational activities such that they maintain and develop their interest in chemistry and science in general. We will consider that our work is good if the students find their experience with science interesting, intriguing, and informative.