Fall 2007 Journal Club (Graduate Research Seminar)-Department of Biological Sciences - Carnegie Mellon University

Fall 2007 Journal Club

(Graduate Research Seminar)

Journal club is held in the Conference Room of the Mellon Institute at 12:30 p.m. on Wednesdays unless otherwise indicated.




Aug 29 Shantanu Bhattacharyya "RNA editing redirects miRNA to new silencing targets"
Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs Kawahara et.al. Science 23 February 2007:
Vol. 315. no. 5815, pp. 1137 - 1140
  Dara Brown "Hope for Alzheimer's - combating Amyloid-Beta with scFvs" Levites Y, Jansen K, Smithson LA, Dakin R, Holloway VM, Das P, Golde TE (2006). Intracranial Adeno-Associated Virus-Mediated Delivery of Anti-Pan Amyloid Beta, Amyloid Beta40, and Amyloid Beta42 Single Chain Variable Fragments Attenuates Plaque Pathology in Amyloid Precursor Protein Mice. J Neurosci 26(46): 11923-11928.
Sept. 5
Saksham Chandra "A functional circuit underlying male sexual behavior in the female mouse brain"
Kimchi, T. Xu, J. & Dulac C. A functional circuit underlying male sexual behavior in the female mouse brain. Nature (advance online publication 5 August 2007).
  Nathan Urban "New kids on the block"
Mizrahi A. Dendritic development and plasticity of adult-born neurons in the mouse olfactory bulb.
Nat Neurosci. 2007 Apr;10(4):444-52. Epub 2007 Mar 18.
Sept. 12
Shantanu Ganguly "Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury"
Parr et al, Bone Marrow Transplantation; May 2007.
  John Holleran "Traffic at the plasma membrane: insulin gives glucose transporter the green light"
Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S, Corvera S, Fogarty KE, Czech MP. Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on
adipocyte plasma membranes. Mol Cell Biol. 2007 May;27(9):3456-69. Epub 2007 Mar 5.
Sept. 19
Elmer Ker "Primary cilia mediate mechanosensing in bone cells by a
calcium-independent mechanism"

Proceedings of the National Academy of Sciences, 104: 33, 13325–13330, August 14, 2007.
  Jonathan Jarvik "Where can I change?"
Wang CL, Harper RA & Wabl M. Genome-wide somatic hypermutation. Proceedings of the National Academy of Sciences. USA 101, 7352–7356, 2004.
Sept. 26
Brenna McCauley "How the zebrafish got its stripes: Melanogenesis in Danio species"
Mills GM, Nuckles RJ, and Parichy DM. Deconstructing evolution of adult phenotypes: genetic analyses of kit reveal homology and evolutionary novelty during adult pigment pattern development of Danio fishes. Development 134: 1081-1090, 2007.
  Nicole Marthaler "Ten_m3 blind mice: molecular cue regulates specified mapping in the visual system"
Leamey et al. Ten_m3 Regulates Eye-Specific Patterning in the Mammalian Visual Pathway and Is Required for Binocular Vision. PLoS Biology Vol 5(9):2077-92, 2007.

Oct. 3

Parker Mills "Function and structure of iron regulatory protein 1"
Walden WE et al. Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. Science 314:1903-8, 2006.
  Brooke McCartney "Don't quit your day job"
Balklava Z. et al. Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nature Cell Biology 9(9)1066-1073, 2007.
Oct. 10
Jeanne Morin-Leisk "The tail end of membrane insertion"
Stefanovic S and Ramanujan S. HegdeIdentification of a Targeting Factor for Posttranslational Membrane Protein Insertion into the ER. Cell 128, 1147-1159, March 23, 2007.
  Kalin Vasilev "Anti-aging"
Powers RW, Kaeberlein M, Caldwell SD, Kennedy BK and Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes & Dev 20: 174-184, 2006.
Oct. 17
Jing Wen "Fear memory in the brain"
Reijmers LG, Perkins BL, Matsuo N, Mayford M.
Localization of a stable neural correlate of associative memory.
Science, 317(5842):1230-3, 2007 Aug 31.
  Fred Lanni "A tale of synchrony"
Riedel-Kruse, et al. Synchrony dynamics during initiation, failure, and rescue of the segmentation clock. Science 317 (9/28): 1911-15, 2007.
Oct. 24 Smita Yadav "Nuclear cover-up"
Anderson DJ and Hetzer MW. Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum. Nature Cell Biology, 9(10): Oct 2007.
  Qi Yan "Akt-ivity in mice"
Zhang L, et al. Molecular imaging of Akt kinase activity. Nature Medicine. 13(9):1114-9, Sept 2007.
Oct. 31 Bradley Yates "Supercharge me"
Lawrence MS, Phillips KJ, Liu DR. Supercharging proteins can impart unusual resilience. Journal of the American Chemical Society. 22;129(33):10110-2. Aug 2007.
Nov. 7 Margarida Anjos "Get in shape with shavenbaby"
McGregor, A. P. et al. Morphological evolution through multiple cis-regulatory mutations at a single gene. Nature. 448:587-591. 2007
  Mengning Zhou "APC2, what is your alibi?"
Nov. 14 Panagiotis Papasaikas "The pleasure of all things Bayesian"
Mon, Nov. 19
(12:30-2:00pm in the Social Room)
Rotation Reports 1. Kaitlyn Dykstra, Advisor: Jonathan Minden

2: Ashrifia Gogo, Advisor: Jonathan Minden

3: Ayshwarya Subramanian, Advisor: Robert Murphy

4: David Whitney, Advisor: Eric Ahrens

5: Timothy Jarvela, Advisor: Adam Linstedt

6: Megha Kapur, Advisor: Adam Linstedt

7: John Mkpa, Advisor: Alison Barth

Tue, Nov. 20
(3:30-5:00pm in the Auditorium)
Rotation Reports 1. Mohammad Qureshi, Advisor: Justin Crowley

2: Kiran Rafiq, Advisor: Charles Ettensohn

3: Merissa Scozio, Advisor: Justin Crowley

4: Jesse Sheehan, Advisor: Carl Olson

5: Emily Furbee, Advisor: John Woolford

6: Anmol Grover, Advisor: Javier Lopez

7: Jason Talkish, Advisor: Javier Lopez

Nov. 28 Debrup Sengupta "GRASPing the membranes"
  Sonal Shruti "Tail tales: Regulation of BK channel beta subunits after seizure"
Dec. 5 Brett Benedetti

"Single and loving it, OR What a difference a day makes"

  Tamara Berdyyeva "Shocking order of things, OR Involvement of the supplementary eye field in representing object rank: evidence from recording and electrical stimulation"