Fall 2004 Journal Club
(Graduate Research Seminar)
Journal club is held in the Conference Room of the Mellon Institute at
3:30 on Wednesdays unless otherwise indicated.
|Sept. 8||Tamara Berdyyeva||"Sleepy issue, or too much is never enough" Cirelli C, Gutierrez CM, Tononi G. Neuron. January 8, 2004 Vol. 41, 35-43, Extensive and divergent effects of sleep and wakefulness on brain gene expression"|
|Brooke McCartney||"A link between death and migration: crawling posterior to the border."
Geisbrecht ER, Montell DJ. Cell. July 9, 2004.Vol. 118, 111-125, A Role for Drosophila IAP1-Mediated Caspase Inhib
|Sept. 15||Yusong Guo||"Cell cycle regulation of central spindle assembly Nature. 2004 Aug 19; 430:908-13".|
|Peter Berget||"Dox or Die!" SP-B deficiency causes respiratory failure in adult mice.
Melton KR, Nesslein LL, Ikegami M, Tichelaar JW, Clark JC, Whitsett JA,
Weaver TE Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L543-9. Epub 2003 Mar 14.
|Sept. 22||Krishnan Padmanabhan||"The neuron that colapsed time because it understood space....ohhhhhh" Regulation of dendritic protein synthesis by miniature synaptic events.
Sutton MA, Wall NR, Aakalu GN, Schuman EM.
Science. 2004 Jun 25;304(5679):1979-83
|Nathan Urban||"New tricks for new neurons." Hoglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, Hirsch EC. Related Articles, Links
Dopamine depletion impairs precursor cell proliferation in Parkinson
disease. Nat Neurosci. 2004 Jul;7(7):726-35.
|Sept. 29||Kaustubh Sinha||"The atomic architecture of a gas channel" Mechanism of Ammonia Transport by Amt/MEP/Rh: Structure of AmtB at 1.35 Å . Khademi et. al. SCIENCE 2004 Sep 10 Vol.305 (1590)|
|Fred Lanni||"Big Phil'n da boys got to go easy around Junior - sez Mom." Kindzelskii AL, Huang JB, Chaiworapongsa T, Fahmy RM, Kim YM, Romero R, Petty HR (2002). Pregnancy alters glucose-6-phosphate dehydrogenase trafficking, cell metabolism, and oxidant release of maternal neutrophils.
J Clin Invest. 110:1801-1811.
Kindzelskii AL, Ueki T, Michibata H, Chaiworapongsa T, Romero R, Petty HR (2004).6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy. J Immunol. 172:6373-6381.
|Oct. 6||Rebecca Webb||"Fishing and Gaming- That doesn't sound like work to me!" Rogers, GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, Vale RD, Scholey JM, Sharp DJ. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature 2004, 427,364-370.|
|Russell Schwartz||"Flip-Flopping Factors" Luscombe NM, Babu MM, Yu H, M. Snyder,Teichmann SA, Gerstein M."Genomic analysis of regulatory network dynamics reveals large topological changes." Nature 431:308-312, 2004.|
|Oct. 13||Cancelled||- No Journal Club today -|
|Oct. 20||Jingyu Zhang||"Bud says YES to RB, RB says NO to bud" CDK activity antagonizes Whi5, an
inhibitor of G1/S transcription in yeast. Cell, Vol. 117, 899-913, June 25, 2004.
|Amy Csink||"Meet me at the factory." Osborne CS, Chakalova L, Brown KE, Carter D, Horton A, Debrand E,
Goyenechea B, Mitchell JA, Lopes S, Reik W, Fraser P. Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet. 2004 Oct;36(10):1065-71
|Oct. 27||Tiequan Zhang||"Hit once, hit twice, what is the difference?"Nowak MA, Franziska M, Komarova NL, Iwasa Y
Evolutionary dynamics of tumor suppressor gene inactivation PNAS 2004 Jul;101(29):10635-10638
|John Woolford||"Anticipating growth:paradox found....How do cells determine how large to grow?" Jorgensen P, Rupeš I, Sharom JR, Schneper L, Broach JR, Tyers M
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size Genes and Dev. 2004;18:2491-2505
|Nov. 3||Sandra Zimmerman|
|Nov. 10||Roger Clem||"Anticipating growth:paradox found....How do cells determine how large to grow?"|
|Jon Minden||"SCAMed again" Wojtowicz WM, Flanagan JJ, Millard SS, Zipursky SL, and Clemens JC. Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell 118, 619-633, 2004.|
|Nov. 17||Timothy Feinstein||"Stop Right There! Acute Inhibitors as a Tool to Study Protein Kinases Involved in Mitotic Golgi Vesiculation."|
|Tina Lee||"The faces of Shugoshin" Kitajima TS, Kawashima SA, Watanabe Y. The conserved kinetechore protein shugoshin protects centromeric cohesion during meiosis. Nature 427, 510-517, 2004. Salic A, Waters, JC, Mitchison TJ. Vertebrate shugoshin links sister centromere cohesion and kintechore microtubule stability in mitosis. Cell 118, 567-578, 2004.|
|Dec. 1||Anupam Goyal
||"Do or Die"|
|Justin Crowley||"Green means go, BLUE means stop; are photoisomerizable K+ channels a flash of brilliance?" Banghart, M., Borges, K., Isacoff, E.,Trauner, D., Kramer, R.H. "Light-activated ion channels for remote control of neuronal firing." Nature Neuroscience 12(7): 1381-1386, 2004.|
|Dec. 8||Juchang Hua||"SLIF - Subcellular Location Image Finder"|
|Gordon Rule||"Okazaki Fragments Revised - Why are DNA-RNA Junctions Never Formed?" Pascal et al. "Human DNA ligase I completely encircles and partially unwinds nicked DNA." Nature 432, 473-478, 2004.|