Spring 2015 Journal Club (Graduate Research Seminar)-Department of Biological Sciences - Carnegie Mellon University

Spring 2015 Journal Club

(Graduate Research Seminar)

Journal club is held in the Conference Room of the Mellon Institute at 3:30 p.m. on Wednesdays unless otherwise indicated.

Date

Speaker

Topic

1/21 Tanvi Shashikant From Genome to Morphology: The Dissection of a Developmental Gene Regulatory Network
Zhongling Sun Regulation of Skeletal Morphogenesis by TGF-β Signaling in the Sea Urchin Embryo
1/28 Daniel Shiwarski Unlocking the DOR to the surface: Regulated Surface Delivery of the δ-Opioid Receptor (DOR)
David Hackney Enzymes on the move in ways you probably did not expect
2/4 Ardon Shorr How does gravity affect gene expression? A proteomic approach
Chien Ho Accidental Discovery in Research
2/11 Pieter Spealman N-terminal extensions: Protein Isoforms Revealed Under Stress
Maureen Stolzer Evolution of the Metazoan Protein Toolkit
2/18 Shanna Bowersox A Drug Selective Phosphoswitch Regulates mu-Opioid Receptor Recycling
John Woolford A novel mechanism for translational control in mammalian development....specialized ribosomes?

Xue S, Tian S, Fujii K, Kladwang W, Das R, Barna M. RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation. Nature. 2015 Jan 1;517(7532):33-8.
2/25 Christopher Pratt Red Light, Green Light: Two-Color Fluorogen Labeling Unveils BK Channel Trafficking
Brooke McCartney

Making connections: how "interactomics" teaches us about the inner lives of cells

Nicolas Preitner, Jie Quan, Dan W. Nowakowski, Melissa L. Hancock, Jianhua Shi, Joseph Tcherkezian, Tracy L. Young-Pearse, John G. Flanagan. APC Is an RNA-Binding Protein, and Its Interactome Provides a Link to Neural Development and Microtubule Assembly. Cell, Volume 158, Issue 2, 17 July 2014, Pages 368-382.

3/4 Rotation Talks

Dan Ackerman - “Colocalization of β2AR with TGN46, a Marker for the Trans-Golgi Network”

Amber Lucas - "Proteome sample cleanup using biotinylated proteins and polymer caged Avidin"

Surya Aggarwal - "Streptococcus pneumoniae Penicillin Resistance: Genotypes, Phenotypes & Fitness Costs"

Stephanie Biedka - "The Role of Ribosomal Proteins in 5S rRNA Rotation”

David Chen - "Effects of NGF Treatment on Delta-Opioid Receptor – Rab2/6 Interaction"

Hannah Kim - "A Journey to Find Phenotypes Associated to Gene Knockouts in Streptococcus pneumoniae"

Ian Fucci - “Probing dynamics of mutant and wild-type human thymidylate kinase using NMR spectroscopy”

Jian Ming Khor - "Targeting of Dishevelled in Early Embryogenesis"

Rolando Cuevas - "The CORVET Subunit VPS8 regulates recycling of β2 Adrenergic Receptor"

Alan Shteyman - “To Impute or Not To Impute: That is my Rotation Question”

Elena Shuvaeva - "The role of ribosomal protein L28 in late stage large subunit assembly"

Meiqi Wang - "Image-derived generative models of cellular organization"

Nathaniel Williams - "Defining subnetworks within the mouse visual system"

Andrew Wolff - "Atlastin disease mutation alters mitochondrial distribution"
3/11 Spring Break
3/18 Karen Kormuth A Novel Mode of Homologous PNA Hybridization to G-quadruplex DNA
Marcel Bruchez

Long Ago and Far Away:  Presynaptic Activity Regulates Gene Expression at the Soma

Daniela Ivanova, Anika Dirks, Carolina Montenegro-Venegas, Cornelia Schöne, Wilko D Altrock, Claudia Marini, Renato Frischknecht, Denny Schanze, Martin Zenker, Eckart D Gundelfinger & Anna Fejtova. Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. The Embo Journal, 4 Feb 2015.

3/25 Han Lai An Eye Catching Tale: How Gene Transfer Allows Colonization of a New Niche
Jonathan Jarvik Aging and surviving in the tree of life
4/1 Ting Liu Polymorphism of DNA ejection dynamics - not every virion is ready to infect
Marcel Bruchez

Long Ago and Far Away:  Presynaptic Activity Regulates Gene Expression at the Soma

Daniela Ivanova, Anika Dirks, Carolina Montenegro-Venegas, Cornelia Schöne, Wilko D Altrock, Claudia Marini, Renato Frischknecht, Denny Schanze, Martin Zenker, Eckart D Gundelfinger & Anna Fejtova. Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. The Embo Journal, 4 Feb 2015.
4/8 Salini Konikkat New Alleles Reveal Later Functions of Erb1 in Ribosome Assembly
Chuck Ettensohn Regeneration of digits in mice and humans
4/15 John Pettersson Single Molecule Studies of Glutathione S-Transferase
Luisa Hiller The Invisible World: A Source of New Chemistry to Target Superbugs
4/22

Sahil Sangani

Dynamics of a Protein-DNA-Metal Complex
Russell Schwartz Do You Feel Lucky?
4/29 Madhumitha Ramesh Novel Roles for  Eukaryote-Specific rRNA Expansion Segments in Ribosome Biogenesis
Tina Lee Myoblasts perform under pressure

Kim JH, Ren Y, Ng WP, Li S, Son S, Kee, YS, Zhang S, Zhang G, Fletcher
DA, Robinson DN and Chen E. Mechanical Tension Drives Cell Membrane Fusion.
Developmental Cell 32, 561-573, Mar 9, 2015.
5/6 Rotation Talks

Dan Ackerman - “Activity of the ER at sites of endosome tubule fission”

Surya Aggarwal - "Why double you P1 inhibits biofilm formation"

Stephanie Biedka - "The C-terminus of ATL1 inhibits ATL1 GTPase activity in vitro”

David Chen - "Improving Cell Permeability of (R)-Diethylene Glycol-Contacting γ-PNA"

Rolando Cuevas - "Assessing Dishevelled Self-Association During Early Embryogenesis of Lytechinus variegatus"

Hannah Kim - TBA

Ian Fucci - “The Nucleotide-Free Refractory State of Kinesin Motor Domains may be a Molten Globule”

Jian Ming Khor - "The Role of Lunapark in Endoplasmic Reticulum Structuring"

Amber Lucas - "Proteomic analysis of early regeneration in Patiria miniata"

Alan Shteyman - “I think I've seen this Pattern before”

Elena Shuvaeva - "Regulation of β2-adrenergic receptor recycling and resensitization"

Meiqi Wang - "In vivo detection of FAP expression in neurons"

Nathaniel Williams - "Exploring the Effect of Familiarity in the
Visual System"

Andrew Wolff - "Characterization of cell proliferation during sea star regeneration"
5/13 Massimo Trucco Institute of Cellular Therapeutics at Allegheny
General Hospital
Nick Giannoukakis Institute of Cellular Therapeutics at Allegheny
General Hospital