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Neuroscience |
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Eric
T. Ahrens
The Ahrens laboratory develops unique molecular and cellular
MRI probes to visualize gene expression and immune cell trafficking into
the brain. In related efforts, the researchers seek to understand the
homeostasis of metal ions in brain tissues.
Alison
Barth
The Barth group has generated transgenic mice that express fluorescent
proteins in response to neural activity, providing a way to image and
record from activated neural subsets. The laboratory is using this tool
and others to identify specific cortical pathways that are involved in
learning and memory.
Justin
Crowley
The mechanisms underlying the development of neuronal structure
and function in the visual system, including the complex interactions
between neural activity, sensory experience and genetics in the generation
of neuronal circuits, are a prominent area of research in the Crowley
laboratory.
Mark R. Macbeth
The Macbeth lab is interested in the editing, or modification, of mRNAs that encode several neuronal receptors and ion channels. The adenosine to inosine mutations in the mRNA are essential for proper neuronal function, and research in the lab focuses on the regulation of the editing activity by a cell signaling molecule (inositol hexakisphosphate), as well as the effects of RNA editing on the activity of the encoded neural receptors and ion channels.
Carl R. Olson
Researchers in the Olson laboratory study the brain mechanisms of cognition by recording from single neurons in the cerebral cortex of behaving monkeys. Research interests include spatial vision, visual pattern recognition and executive control.
Joel
R. Stiles
The Stiles laboratory uses spatially realistic 3-D models, unique Monte
Carlo simulation algorithms (MCell), large-scale visualization methods
(DReAMM), and high performance computing to study synaptic transmission
and biochemical signaling pathways. Present projects focus on postsynaptic
topology and quantal current variability at the mammalian neuromuscular
junction, as well as presynaptic calcium dynamics and neurotransmitter
release at the amphibian neuromuscular junction.
Nathan
N. Urban
The Urban laboratory studies excitatory and inhibitory circuits
in the mouse olfactory bulb using paired recordings and optical imaging
to understand how these circuits both transform and are dynamically altered
by patterns of odor-evoked activity.
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