Peter B. Berget
Associate Professor
The Berget laboratory uses molecular biology techniques to engineer single chain antibody fragments to react to specific intracellular signals, thus making them into "biosensors" for networks and pathways.
Faculty Webpage |
Charles A. Ettensohn
Professor
The Ettensohn laboratory studies complex gene regulatory networks that underlie embryonic development and uses gene knockdown techniques to dissect the developmental functions of genes.
Faculty Webpage |
Jonathan W. Jarvik
Associate Professor
In the Jarvik laboratory, viral vectors are used to create mammalian cell lines expressing reporter-tagged proteins that exhibit native regulation while retaining native biochemical and structural integrity.
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Adam D. Linstedt
Professor
The Linstedt group is investigating molecular mechanisms that establish and maintain the membrane-bounded compartments of the secretory and endocytic pathways. Approaches include permeabilized cell assays, biochemical reconstitutions, cell imaging techniques and molecular genetic experiments.
Faculty Webpage |
A. Javier López
Associate Professor
The Lopez group employs genetic, genomic, and molecular approaches in Drosophila to characterize regulatory mechanisms for alternative splicing and how they influence development. The role of recursive splicing in the expression and evolution of large transcription units are principal areas of study.
Faculty Webpage |
Mark R. Macbeth
Assistant Professor
The Macbeth lab is interested is interested in RNA-protein interactions, specifically those that involve ADARs, or Adenosine deaminases that act on RNA. We use structural, biochemical and genetic methods to characterize the 3-D ADAR structure, its enzymatic mechanism, and the regulation of its activity.
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Brooke M. McCartney
Assistant Professor
In the field of developmental genetics, the McCartney laboratory uses the powerful genetic tools available in Drosophila to investigate questions of signal transduction and cytoskeletal organization.
Faculty Webpage |
Jonathan S. Minden
Professor
Researchers in the Minden laboratory are using genetics and molecular biology approaches to study to role certain genes and proteins play in controlling how cells change shape during Drosophila embryogenesis. They are also using the same methods to study early protein changes during developmentally regulated cell death.
Faculty Webpage |
Aaron P. Mitchell
Professor
The Mitchell laboratory applies new gene disruption and overexpression strategies to identify C. albicans genes that govern pathogenesis and to understand their functional relationships, and to understand the mechanistic relationships in a fungal endosome-associated signal transduction pathway.
Faculty Webpage |
Manojkumar A. Puthenveedu
Assistant Professor
The Puthenveedu laboratory uses molecular and functional genetic tools to study membrane trafficking events that regulate signaling by G protein-coupled receptors in model cells and neurons.
Faculty Webpage |
Russell S. Schwartz
Associate Professor
The Schwartz laboratory is developing of mathematical models and computational methods for analyzing genetic polymorphism data, and applying them to problems in disease association study design.
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John L. Woolford
Acting Department Head and Professor
The Woolford group is studying the biogenesis of ribosomes in yeast. After discovering that expression of ribosomal protein genes is coupled with assembly of ribosomes, they have been developing methods for purification and characterization of ribosome assembly intermediates as well as complexes involved in regulating ribosomal protein gene expression.
Faculty Webpage |
Eric Xing
Affiliated Biological Sciences Faculty
Eric Xing develops statistical models and machine learning algorithms for biological network inference and characterization, cis-regulatory module decoding, regulatory evolution modeling, quantitative trait locus mapping, genome polymorphism patterning, and population genetic analysis. He is also applying these quantitative approaches to investigate the mechanisms of breast cancer development and metazoan morphagenesis.
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