Charles A. Ettensohn
Professor
The Ettensohn laboratory studies the cellular and molecular mechanisms of morphogenetic processes (cell migration, epithelial folding, cell-cell fusion, and biomineralization) in the sea urchin embryo. The laboratory also studies the role of the canonical Wnt signaling pathway in early embryonic polarity.
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David D. Hackney
Professor
The Hackney laboratory investigates the regulation of kinesins by formation of a folded quaternary structure, as well as the influence of auxiliary microtubule binding sites on the motile properties of the motors and how it relates to their in vivo function.
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Veronica F. Hinman
Assistant Professor
The Hinman laboratory studies gene regulatory networks (GRNs) using models that consider not only the expression domains and function of many regulatory genes (mostly transcription factors), but more importantly, their inter-relationships.
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Chien Ho
Professor
Using rodent models for organ transplantation, the Ho laboratory studies the migration and accumulation of immune cells within rejecting kidney, heart, and lung tissues. Non-invasive MRI methods are used to analyze cellular behavior.
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Jonathan W. Jarvik
Associate Professor
The Jarvik group is developing gene-tagging methods that enable the observation and quantitation of the location, abundance, and dynamics of individual protein species in living cells and tissues.
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Frederick Lanni
Associate Professor
Regulation of mechanical activity in the actin-based cytoskeleton is a major interest area in the Lanni laboratory.
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Tina H. Lee
Associate Professor
Research in the Lee laboratory focuses on the mechanism of coated vesicle formation from the mammalian endoplasmic reticulum and how this first committed step in protein secretion is regulated by physiological cues.
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Adam D. Linstedt
Professor
The Linstedt group is investigating molecular mechanisms that establish and maintain the membrane-bounded compartments of the secretory and endocytic pathways. Approaches include permeabilized cell assays, biochemical reconstitutions, cell imaging techniques and molecular genetic experiments.
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A. Javier López
Associate Professor
The López laboratory uses various model systems to study how splicing of pre-mRNA is regulated in vivo and how alternative splicing influences development and cellular function. Recursive splicing mechanisms and their role in expression of very large transcription units are major areas of study.
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Brooke M. McCartney
Assistant Professor
Investigating mechanisms of signal transduction and cytoskeletal organization using the APC family of tumor suppressors as a model is a principal interest in the McCartney laboratory.
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Jonathan S. Minden
Professor
The Minden laboratory is using proteomics and time-lapse microscopy to study how cells change shape during Drosophila embryogenesis.We are also using the same methods to study early protein changes during developmentally regulated cell death.
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Aaron P. Mitchell
Professor
The Mitchell laboratory is interested in diverse signal transduction pathways that govern environmental sensing, biofilm formation, and pathogenesis in the fungal pathogen C. albicans and the model yeast S. cerevisiae.
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Robert F. Murphy
Professor
The Murphy group focuses on location proteomics, using fluorescence microscopy and computational methods to analyze subcellular location on a proteome-wide basis.
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Manojkumar A. Puthenveedu
Assistant Professor
The Puthenveedu laboratory studies how membrane trafficking regulates receptor-mediated signaling in living cells. We focus on trafficking events that regulate signaling by G protein-coupled receptors involved in drug addiction.
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Alan S. Waggoner
Professor
Research has focused on development of fluorescence-based detection systems for biology and biotechnology. These include fluorescent probes and imaging microscopes for studying protein and nucleic acid regulatory pathways in living cells and tissues.
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John L. Woolford
Acting Department Head and Professor
Researchers in the Woolford group investigate mechanisms of ribosome assembly and how control of cell growth and cell proliferation are regulated in concert with ribosome biogenesis.
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