Biotechnology-Department of Biological Sciences - Carnegie Mellon University

Biotechnology

Bruce T. Armitage

Affiliated Biological Sciences Faculty

As part of the Molecular Biosensors and Imaging Center (MBIC), the Armitage group is developing fluorescent biosensors for detecting nucleic acid and protein targets inside of cells or in biological samples.
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Marcel P Bruchez

Associate Professor

The Bruchez Group, as part of the Molecular Biosensors and Imaging Center, is developing new imaging and labeling approaches using genetically targeted fluorophores.  These approaches enable sensitive fluorescence imaging of living cells at resolutions approaching molecular length-scales, using a combination of single molecule localization and stimulated emission depletion microscopies. 
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Chien Ho

Professor

The Ho laboratory is interested in hemoglobin therapeutics and the design of novel recombinant hemoglobins as potential hemoglobin-based oxygen carriers; they also develop novel non-invasive MRI-based methodology to detect graft rejection following solid organ transplantation in animal models.
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Jonathan W. Jarvik

Associate Professor

The Jarvik laboratory is developing tools that provide for rapid delivery and expression of naturally regulated genes that express reporter-tagged proteins in mammalian cells.
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Frederick Lanni

Associate Professor

In the Lanni laboratory, timelapse and optical-sectioning microscopy are used for the study of cytoskeletal organization.
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Jonathan S. Minden

Professor

The Minden laboratory has developed several methods for comparative proteomics, starting with Difference Gel Electrophoresis (DIGE). The lab is currently developing a high dynamic range imaging system to detect proteins over a million-fold concentration range, as well as developing new devices for protein isolation.
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Aaron P. Mitchell

Professor

The Mitchell laboratory is developing new methodology to detect eukaryotic protein-protein interactions.
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Manojkumar A. Puthenveedu

Assistant Professor

The Puthenveedu laboratory is interested in developing new probes and methodologies based on high-resolution microscopy to study receptor-mediated signaling in living cells.
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Nathan N. Urban

Department Head

The Urban laboratory is working on the development of novel techniques for electrical and optical recording from single neurons and populations of neurons in vivo and in vitro.
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Alan S. Waggoner

Maxwell H. and Gloria C. Connan Professor of Life Sciences

Research has focused on the development of fluorescence-based detection systems for biology and biotechnology. Our current focus applies the Fluorogen-Activating Protein (FAP) technology to develop novel biosensors of protein interactions and pathway regulation within living cells.
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