Structural Biologist Mark Macbeth Joins the Department of Biological Sciences
The growing field of structural biology at Carnegie Mellon just got a new member. Mark Macbeth, who earned a Ph.D. in Biochemistry and Molecular Biology from University of Chicago, joined the Department of Biological Sciences on May 1, 2007. His work will enhance structural biology research in the Department.
Macbeth’s laboratory will study the structure and the function of adenosine deaminases that act on RNA (ADARs), a class of enzymes responsible for regulating nervous system function. He studies ADARs from two angles: a biochemical angle, using mutagenesis, and structural angle, using X-ray crystallography.
Macbeth’s first goals as a Carnegie Mellon faculty member are to find out what an ADAR looks like when it’s bound to RNA. He anticipates much collaboration within the Department and with the new joint program in Structural Biology and Biophysics between Carnegie Mellon and the University of Pittsburgh. “There are many faculty who have never worked on structural problems before, who are interested in working together,” he said. “ I can’t wait to start!”