03-232: Biochemistry I
This course provides an introduction to the application of biochemistry to biotechnology. The functional properties of amino acids, nucleotides, lipids, and sugars are presented. This is followed by a discussion of the structural and thermodynamic aspects of the organization of these molecules into higher-order structures, such as proteins, nucleic acids, and membranes. The kinetics and thermodynamics of protein-ligand interactions are discussed for non-cooperative, cooperative, and allosteric binding events. The use of mechanistic and kinetic information in enzyme characterization and drug discovery are discussed. Topics pertinent to biotechnology include: antibody production and use, energy production in biochemical systems, expression of recombinant proteins, and methods of protein purification and characterization. The course is an alternate to 03-231.
The above link is not for students enrolled in the course, but gives anyone who is interested an idea of the course material.
Spring: 9 units
Prerequisites: 09-217 or 09-219
The requirement for 09-217 or 09-219 (organic chemistry) can be waived with supplementary readings, please contact the instructor at email@example.com.