03-232: Biochemistry I-Department of Biological Sciences - Carnegie Mellon University

03-232: Biochemistry I

This course provides an introduction to the application of biochemistry to biotechnology. The functional properties of amino acids, nucleotides, lipids, and sugars are presented. This is followed by a discussion of the structural and thermodynamic aspects of the organization of these molecules into higher-order structures, such as proteins, nucleic acids, and membranes. The kinetics and thermodynamics of protein-ligand interactions are discussed for non-cooperative, cooperative, and allosteric binding events. The use of mechanistic and kinetic information in enzyme characterization and drug discovery are discussed. Topics pertinent to biotechnology include: antibody production and use, energy production in biochemical systems, expression of recombinant proteins, and methods of protein purification and characterization.

The above link is not for students enrolled in the course, but gives anyone who is interested an idea of the course material.

**The course is an alternate to 03-231.
Spring: 9 units
Prerequisites: 09-217 or 09-219. [The requirement for 09-217 or 09-219 (organic chemistry) can be waived with supplementary readings, please contact the instructor Gordon Rule.]
Corequisites: 09-106 or 06-221.